This seems a really week connection. > In bacteria grown in well-oxygenated laboratory conditions, the antidepressants caused the cells to generate reactive ox

This seems a really week connection. > In bacteria grown in well-oxygenated laboratory conditions, the antidepressants caused the cells to generate reactive oxygen species: toxic molecules that activated the microbe’s defence mechanisms. Most prominently, this activated the bacteria’s efflux pump systems, a general expulsion system that many bacteria use to eliminate various molecules, including antibiotics. This probably explains how the bacteria could withstand the antibiotics without having specific resistance genes. So the study was: * Done in a petri dish * Done in an environment dissimilar to the human body * Showed an adaptation to the environment unrelated to antibiotic resistance Showing adaptation "efflux pumps" for oxygen removal and claiming it's applicable to antibiotics seems like claiming yoga mats are made from jet fuel because they both contain water. It would be really interesting if they tested a null here which I don't see noted anywhere. If the adaptation happened in the oxygen rich environment without the antibiotic it would indicate that antibiotics are not causal.