4 ms·

Flash reactions: * You could identify fentanyl passed off as heroin, cocaine, etc because they don't work as well. * "Damn this cocaine is weak. Maybe I need

Flash reactions: * You could identify fentanyl passed off as heroin, cocaine, etc because they don't work as well. * "Damn this cocaine is weak. Maybe I need to take more" - I could imagine this leading to more fentanyl overdoses. * Something like this happened in neuromancer.

elil17 4y ago
Opioid overdoses are typically due how opioids effect the brain, so this would prevent fentanyl from contributing to and overdose.
- pessimizer 4y ago
  Opioid overdoses are typically due to overestimation of one's tolerance or underestimation of the strength of the drug being taken, and what you are responding to is a way that a weakened fentanyl effect could lead to that.
  - elil17 4y ago
    You could still OD, but it would not be a fentanyl OD, because the fentanyl in the drug would not be able to interact with the brain. If you took this vaccine, it seems like you would be just as likely to OD from heroin as you would from fentanyl+heroin.
- orblivion 4y ago
  Yeah that did cross my mind. I wonder if it really blocks it at the same level that you're talking about.
  - elil17 4y ago
    That is part of the goal of the vaccines, but I don't think there is enough trial data to know yet.
version_five 4y ago
> Something like this happened in neuromancer. Right, and Case bought betaphenethylamine instead of speed which was way harsher. That's exactly what is going to happen, some more potent drug that escapes the vaccine is going to get more popular. It's a bandaid solution that ignores the root cause (drug prohibition)
- actionfromafar 4y ago
  Wait, what? Selling fentanyl as candy in every street corner shop is going to fix this?
  - klyrs 4y ago
    There is a broad gulf between selling something like candy and criminalizing its possession. You need to be of-age to buy beer. Sudafed is sold OTC but with strict limits. You need a prescription to get many pharmaceuticals.
    - amalcon 4y ago
      The reason for the strict limits on pseudoephedrine is because of its use in the manufacture of (prohibited) methamphetamine, so that's a poor example. Prescription drugs are also a bad example because fentanyl (and most other opioids) are already available with a prescription in most of the world. Alcohol and nicotine are the only real middle ground in the US (maybe cannabis, but that's in a paradoxical legal status right now). Neither really seems to be in a "solved" state. Though I concede that at least alcohol and nicotine seem to be in a better state than fentanyl.
  - freedomben 4y ago
    I really don't undertand this binary thinking regarding drugs. It seems like there's at least a third option in there somewhere between "ban it all and everything related and lock people up for decades if they touch the stuff" and "put it in a Pez dispenser and give every elementary school student a 12 tab slider with lunch every day." We don't do that with alcohol or weed, I don't see why that's the first (and often only) option that comes to people's minds when suggesting some form of legalization.
sterlind 4y ago
actually have a friend who nearly died from snorting fentanyl passed off as cocaine. fortunately an ambulance got there in time and saved him with narcan. his doctor friend also snorted coke with him, was carrying narcan in her purse and managed to Pulp Fiction herself on the way down. fentanyl is scary stuff.
simonebrunozzi 4y ago
> * Something like this happened in neuromancer. You just reminded me that I want to re-read it soon.

elil17 4y ago

Opioid overdoses are typically due how opioids effect the brain, so this would prevent fentanyl from contributing to and overdose.

pessimizer 4y ago
Opioid overdoses are typically due to overestimation of one's tolerance or underestimation of the strength of the drug being taken, and what you are responding to is a way that a weakened fentanyl effect could lead to that.
- elil17 4y ago
  You could still OD, but it would not be a fentanyl OD, because the fentanyl in the drug would not be able to interact with the brain. If you took this vaccine, it seems like you would be just as likely to OD from heroin as you would from fentanyl+heroin.
orblivion 4y ago
Yeah that did cross my mind. I wonder if it really blocks it at the same level that you're talking about.
- elil17 4y ago
  That is part of the goal of the vaccines, but I don't think there is enough trial data to know yet.

version_five 4y ago

> Something like this happened in neuromancer. Right, and Case bought betaphenethylamine instead of speed which was way harsher. That's exactly what is going to happen, some more potent drug that escapes the vaccine is going to get more popular. It's a bandaid solution that ignores the root cause (drug prohibition)

actionfromafar 4y ago
Wait, what? Selling fentanyl as candy in every street corner shop is going to fix this?
- klyrs 4y ago
  There is a broad gulf between selling something like candy and criminalizing its possession. You need to be of-age to buy beer. Sudafed is sold OTC but with strict limits. You need a prescription to get many pharmaceuticals.
  - amalcon 4y ago
    The reason for the strict limits on pseudoephedrine is because of its use in the manufacture of (prohibited) methamphetamine, so that's a poor example. Prescription drugs are also a bad example because fentanyl (and most other opioids) are already available with a prescription in most of the world. Alcohol and nicotine are the only real middle ground in the US (maybe cannabis, but that's in a paradoxical legal status right now). Neither really seems to be in a "solved" state. Though I concede that at least alcohol and nicotine seem to be in a better state than fentanyl.
- freedomben 4y ago
  I really don't undertand this binary thinking regarding drugs. It seems like there's at least a third option in there somewhere between "ban it all and everything related and lock people up for decades if they touch the stuff" and "put it in a Pez dispenser and give every elementary school student a 12 tab slider with lunch every day." We don't do that with alcohol or weed, I don't see why that's the first (and often only) option that comes to people's minds when suggesting some form of legalization.

sterlind 4y ago

actually have a friend who nearly died from snorting fentanyl passed off as cocaine. fortunately an ambulance got there in time and saved him with narcan. his doctor friend also snorted coke with him, was carrying narcan in her purse and managed to Pulp Fiction herself on the way down. fentanyl is scary stuff.

simonebrunozzi 4y ago

> * Something like this happened in neuromancer. You just reminded me that I want to re-read it soon.