"A chemical that causes irreversible random brain chemistry changes from a single use sounds like damage has happened" From what I understand, LSD does not cha

"A chemical that causes irreversible random brain chemistry changes from a single use sounds like damage has happened" From what I understand, LSD does not change your brain chemistry directly, but you make deep experiences, and those might change your deep thinking (and therefore the brain chemistry). Opening up your perception to other information channels. But sure, that doesn't mean it must be beneficial. And whether it is a damage I would say depends on the outcome. I know people where LSD was beneficial (solving cluster headache or overcoming addiction) and people where it clearly wasn't (became spaced out weirdos). But everything you do or don't do, comes with a risk. If LSD does not appeal to you, then just don't do it.