I think it can be done. Automated liquid handling and microscopes do exist. We had a confocal microscope in our lab with a robotic arm attached and can automa

I think it can be done. Automated liquid handling and microscopes do exist. We had a confocal microscope in our lab with a robotic arm attached and can automatically image samples. I'm not of the details but the samples are big compared to its field of view so I believe it searches for images with cells before imaging. A lot of experiments are done on these plates with liquid wells. This isn't our model but shows a larger scope with automated robotic arm and a "plate hotel": https://confocal.ccr.cancer.gov/nci-microscopy-core-labs/bethesda/nci-hitif/instrumentation/ https://confocal.ccr.cancer.gov/nci-microscopy-core-labs/bet... I'd go into why we switched from PerkinElmer and their proprietary image format to a GE but thats outside the scope.