I'm biased as the chair, however I would heartily state "yes!" - there's a lot of great stuff on the program that would serve you, not to mention the stuff not

I'm biased as the chair, however I would heartily state "yes!" - there's a lot of great stuff on the program that would serve you, not to mention the stuff not on the program - the open space talks, meeting other hackers and programmers, etc. PyCon is much more than just the talks - and given how cheap admission really is compared to other conferences, it remains a "no duh" type of decision to me.