Because I don’t see much explanation in the comments, I’m going to give my layman understanding of how this works. When an egg and a sperm cell come together t

Because I don’t see much explanation in the comments, I’m going to give my layman understanding of how this works. When an egg and a sperm cell come together to form a new cell, you have two aged cells coming together and somehow from that you get a cell with age zero. In 2006 a Japanese scientist named shinya yamanaka discovered that this age reset actually happens a few days after fertilization, in a process where the epigenome gets reset to baseline by a chemical signal of 4 different factors. Express those factors, and any cell in your body becomes a pluripotent stem cell. For this he won the Nobel prize. What this new research is attempting to do is to do a soft reset of the epigenome- to reset cells to a youthful state without completely reverting them to stem cells. They are also attempting to show that you can cause a mouse to age by inducing breaks in non-coding parts of dna, which indirectly causes degradation of the epigenome. They claim that it is epigenetic drift, not genetic alterations, that causes aging. There’s nothing about this research that seems peculiar to mice. I’m not a biologist but to me, it passes the smell test of at least being plausible- although I think that correctly resetting the epigenome of every different type of cell in the body is going to be a very, very complicated task.