The Sinclair study is pretty contrived work frankly, as the commentary points out. We use cancer treatments in humans which can induce the same sort of DNA dama

The Sinclair study is pretty contrived work frankly, as the commentary points out. We use cancer treatments in humans which can induce the same sort of DNA damage, and those people don’t seem to exhibit dramatically accelerated ageing. This article is much more interesting and well developed IMHO: https://www.cell.com/cell/fulltext/S0092-8674(22)01530-6 https://www.cell.com/cell/fulltext/S0092-8674(22)01530-6 It finds that activation of endogenous retroviruses induces cell senescence and is associated with ageing phenotypes. It also affords a more tractable therapeutic approach eg antivirals or vaccines.