Interesting point. That's definitely visible in the overall art style. But at least regarding the edges and corners of an isometric rectangular cuboid tile, I'

Interesting point. That's definitely visible in the overall art style. But at least regarding the edges and corners of an isometric rectangular cuboid tile, I'm not convinced that there's a meaningful difference between pixel-by-pixel drawing vs non-anti-aliased rendering--the rendering turns out so precisely regular that it might as well have been drawn manually.