E definitely can have a comedown. It's the primary reason I never did it again personally. People's sensitivities to drugs can vary wildly and often dosing rec

E definitely can have a comedown. It's the primary reason I never did it again personally. People's sensitivities to drugs can vary wildly and often dosing recommendations don't consider that. Now back to counting out tiny little beads because my main medicine isn't made in small enough doses for me.