Sibling comments point out some pretty serious conditions that have been caused by antibiotic resistance. However, antibiotic resistance is more likely to cause

Sibling comments point out some pretty serious conditions that have been caused by antibiotic resistance. However, antibiotic resistance is more likely to cause isolated problems than pandemics. We haven't had antibiotics for very long, and most of the pandemics before we had them were viral, not bacterial. However, before we had antibiotics, we had the problem that cuts, scratches, surgery, and similar could get infected, and then you would lose a limb or likely die. We are slowly returning to that state. We live with a huge amount of bacteria around us, and in our guts. Our skin generally protects us from them very well, but those same bacteria that are harmless outside the body can kill when inside the body. Antibiotics not only improved survival rates from silly trivial injuries. They enabled a whole world of surgical interventions, because after surgery you can just give antibiotics to kill off any inadvertent infection you may have introduced. (Yes, sterile operating conditions help too.)