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Fluoroquinolone Antibiotics such as Cipro are often given to animals because they are cheap. They are in no way at all safe for people or animals. Sadly as the

Fluoroquinolone Antibiotics such as Cipro are often given to animals because they are cheap. They are in no way at all safe for people or animals. Sadly as the parent article shows, the FDA doesn't care. The book: "Taking On Big Pharma: Dr. Charles Bennett's Battle" was released this week. I was asked to go with Dr Bennett to speak to members of Congress about the dangers of Fluoroquinolone Antibiotics. As these were a significant contributor to my late wife's suicide. Alas that was right as the world changed at the start of the pandemic and derailed those plans. I have the many FDA warning for Fluoroquinolone Antibiotics here: https://www.kpaddock.com/fq https://www.kpaddock.com/fq People just don't expect side effects like permanent psychoses to come from their antibiotics, as one of the most recent FDA warnings documents. Dr Bennetts new book: https://www.amazon.com/Taking-Big-Pharma-Bennetts-Childrens/dp/1510775412/ref=sr_1_1 https://www.amazon.com/Taking-Big-Pharma-Bennetts-Childrens/... His related interview: https://live.childrenshealthdefense.org/chd-tv/shows/doctors-and-scientists-with-brian-hooker-phd/taking-on-big-pharma--dr-charles-bennetts-battle/ https://live.childrenshealthdefense.org/chd-tv/shows/doctors...

MonkeyClub 4y ago
My condolences for your loss... And thank you for the important information!
notafraudster 4y ago
I'm sorry you lost your wife. My wife had a near-death medical experience last year (a stroke, completely unrelated) and I was never as emotionally empty and destroyed as I was during the ten minutes I thought I lost her and subsequent days worrying about her recovery. You linked an interview with Childrens' Health Defense, an organization whose primary purpose is to argue, categorically, that all vaccinations are dangerous and do not work. They are the largest such organization and their activism has been directly responsible for the growth in resistance to MMR vaccination and later to COVID-19 vaccination. This does not mean that the point about a class of antibiotics is incorrect, and I understand that there's a possibility of "strange bedfellows" here because of the potential agreement on the matter of, uh, "big pharma". As I see it, one possibility is that you linked the CHD article not knowing this. Another possibility is that you linked the CHD article knowing this, but figuring just because they're wrong about vaccines doesn't tarnish them on this issue. Another possibility is that you generally agree with their position on vaccines. I'm not here to judge or change your mind, I'm just telling you that I don't have any prior view about whatever fluoroquinolone antibiotics are. I read the first half of your post wanting to do more investigation. Because of the CHD link inclusion, I am now predisposed not to believe this is a real issue. I am a non-medical social scientist but I have spent a lot of the COVID period publishing work about vaccination. Anti-vaxx stuff is a complete deal-breaker for me. And if your reason for posting was to persuade an audience, I think that's the opposite of what you want.
- gjsman-1000 4y ago
  [flagged]
- camccar 4y ago
  [dead]
- wolfprogramming 4y ago
  [flagged]
- unethical_ban 4y ago
  I agree that when people cite bad sources, it harm's their argument. Yes, dead commenters, the messenger matters. I'll also state I think deleting vaccine skeptics does more harm on HN than good. Let their ignorance be argued, lest they get a persecution complex and dig in more deeply. Only delete, in my opinion, those that cite disinformation or misinformation.
  - magicalist 4y ago
    > Let their ignorance be argued eh, "Disprove [the situation you just said was emotionally gutting] wasn't caused by [nonsense I can write down in 5 seconds but will take 2+ orders of magnitude to respond to]" is pretty classic sealioning/asymmetric trolling. Maybe if they put up a claim with evidence, otherwise it's just low-effort shit posting and not worth much more than a downvote.
- rpaddock 4y ago
  The interview is where it is, which I have no control over. I would have posted Dr. B's interview where ever it was as it is related to the Big Pharma book release. He is considered one of the worlds experts on drug adverse advents. That there are adverse advents with multiple (All?) Big Pharma products is also something I have no control over. I supplied a link to my late wife's page where all the FDA warnings are linked to directly. The other links can be ignored if that is your desire.
- Traubenfuchs 4y ago
culi 4y ago
Interesting. What is the mechanism of action that could be causing this? Are other antibiotics safer in this regard? What are the most commonly used antibiotics? Extremely sorry for your loss
- rpaddock 4y ago
  Thank you. No one really knows what causes these issues. Any other antibiotic is safer. These should have been removed from the market a long time ago. Just read the other comments in this tread for examples.
- Traubenfuchs 4y ago
  > What is the mechanism of action that could be causing this? It is barely understood. Fluoroquinolones are known to cause: Mineral and metal chelation, permanent DNA damage, permanently changed unhealthy epigenetic state changes, increased oxidative stress, permanent damage to mitochondrial DNA. > Are other antibiotics safer in this regard? Besides aminoglycosides like gentamicin which is now liberally used topically because internal usage causes permanent hearing loss, most antibiotics in use generally do not carry a notable risk of lifelong disability. > What are the most commonly used antibiotics? That very much depends on the infection being treated, but let me just guarantee you that there would almost always be an antibiotic available that is a safer alternative to fluoroquinolones. Unfortunately, those antibiotics are generally strictly controlled reserve antibiotics you get IV in a hospital, which you would only get to avoid death or other serious consequences, and just won't get for that treatment resistant gonorrhea, where fluoroquinolones can already indeed be the only freely available alternative. Then there are also substances that just aren't available everywhere, like streptogramins which in Europe you can probably only get in France.
wizee 4y ago
Speaking of Fluoroquinolones and Cipro (Ciprofloxacin) specifically, I personally had bad experiences with it causing tendon damage and severe back pain, though fortunately the damage healed and the back pain cleared within a couple days after stopping my Cipro course early and switching to a different antibiotic.
simonebrunozzi 4y ago
> As these were a significant contributor to my late wife's suicide. I can't even imagine how hard it is for you. I am sorry for your loss.
dml2135 4y ago
I personally experienced the negative affects of fluoroquinolone as well. I did a full course of Cipro and experienced horrible back pain, which was minimized by my doctor until he put me on Levaquin a few weeks later and I had to stop after a few days because the pain was so bad. Six years later I still have some lingering back pain from that incident, seems like it did at least some permanent damage. It was incredibly hard to deal with, on top of the chronic infection causing me to take the antibiotics in the first place. The most frustrating thing was the seeming indifference I got from many (not all) of the doctors I saw about it. Condolences for your loss, and my deepest sympathies.
- aqme28 4y ago
  Ugh Levaquin. One of the well-known side effects is a spontaneous Achilles tendon rupture. Horrifying, and I hated taking it.
  - unethical_ban 4y ago
    That's a terrifying side effect.
    - Traubenfuchs 4y ago
      Don‘t forget about the chronic neuropathy! Some people have hands and feet that will burn and sting until their death. I had to take moxifloxacin and ciprofloxacin at two different times in my life. Besides the achilles, feet and hand tendon pain, both times I would have severe stinging pain in my scalp for months after taking them. Blessed as I am it went away again.
devwastaken 4y ago
The FDA warnings read like any other medication. This article does not point out why this is specifically worse, or how "rare" of an occurrence it is is or isn't. I can't know from this article wether the cause is this antibiotic.
antiatheist 4y ago
https://www.amr.gov.au/about-amr/amr-australia/amr-and-animal-health-australia https://www.amr.gov.au/about-amr/amr-australia/amr-and-anima...

MonkeyClub 4y ago

My condolences for your loss... And thank you for the important information!

notafraudster 4y ago

I'm sorry you lost your wife. My wife had a near-death medical experience last year (a stroke, completely unrelated) and I was never as emotionally empty and destroyed as I was during the ten minutes I thought I lost her and subsequent days worrying about her recovery. You linked an interview with Childrens' Health Defense, an organization whose primary purpose is to argue, categorically, that all vaccinations are dangerous and do not work. They are the largest such organization and their activism has been directly responsible for the growth in resistance to MMR vaccination and later to COVID-19 vaccination. This does not mean that the point about a class of antibiotics is incorrect, and I understand that there's a possibility of "strange bedfellows" here because of the potential agreement on the matter of, uh, "big pharma". As I see it, one possibility is that you linked the CHD article not knowing this. Another possibility is that you linked the CHD article knowing this, but figuring just because they're wrong about vaccines doesn't tarnish them on this issue. Another possibility is that you generally agree with their position on vaccines. I'm not here to judge or change your mind, I'm just telling you that I don't have any prior view about whatever fluoroquinolone antibiotics are. I read the first half of your post wanting to do more investigation. Because of the CHD link inclusion, I am now predisposed not to believe this is a real issue. I am a non-medical social scientist but I have spent a lot of the COVID period publishing work about vaccination. Anti-vaxx stuff is a complete deal-breaker for me. And if your reason for posting was to persuade an audience, I think that's the opposite of what you want.

gjsman-1000 4y ago
[flagged]
camccar 4y ago
[dead]
wolfprogramming 4y ago
[flagged]
unethical_ban 4y ago
I agree that when people cite bad sources, it harm's their argument. Yes, dead commenters, the messenger matters. I'll also state I think deleting vaccine skeptics does more harm on HN than good. Let their ignorance be argued, lest they get a persecution complex and dig in more deeply. Only delete, in my opinion, those that cite disinformation or misinformation.
- magicalist 4y ago
  > Let their ignorance be argued eh, "Disprove [the situation you just said was emotionally gutting] wasn't caused by [nonsense I can write down in 5 seconds but will take 2+ orders of magnitude to respond to]" is pretty classic sealioning/asymmetric trolling. Maybe if they put up a claim with evidence, otherwise it's just low-effort shit posting and not worth much more than a downvote.
rpaddock 4y ago
The interview is where it is, which I have no control over. I would have posted Dr. B's interview where ever it was as it is related to the Big Pharma book release. He is considered one of the worlds experts on drug adverse advents. That there are adverse advents with multiple (All?) Big Pharma products is also something I have no control over. I supplied a link to my late wife's page where all the FDA warnings are linked to directly. The other links can be ignored if that is your desire.
Traubenfuchs 4y ago

culi 4y ago

Interesting. What is the mechanism of action that could be causing this? Are other antibiotics safer in this regard? What are the most commonly used antibiotics? Extremely sorry for your loss

rpaddock 4y ago
Thank you. No one really knows what causes these issues. Any other antibiotic is safer. These should have been removed from the market a long time ago. Just read the other comments in this tread for examples.
Traubenfuchs 4y ago
> What is the mechanism of action that could be causing this? It is barely understood. Fluoroquinolones are known to cause: Mineral and metal chelation, permanent DNA damage, permanently changed unhealthy epigenetic state changes, increased oxidative stress, permanent damage to mitochondrial DNA. > Are other antibiotics safer in this regard? Besides aminoglycosides like gentamicin which is now liberally used topically because internal usage causes permanent hearing loss, most antibiotics in use generally do not carry a notable risk of lifelong disability. > What are the most commonly used antibiotics? That very much depends on the infection being treated, but let me just guarantee you that there would almost always be an antibiotic available that is a safer alternative to fluoroquinolones. Unfortunately, those antibiotics are generally strictly controlled reserve antibiotics you get IV in a hospital, which you would only get to avoid death or other serious consequences, and just won't get for that treatment resistant gonorrhea, where fluoroquinolones can already indeed be the only freely available alternative. Then there are also substances that just aren't available everywhere, like streptogramins which in Europe you can probably only get in France.

wizee 4y ago

Speaking of Fluoroquinolones and Cipro (Ciprofloxacin) specifically, I personally had bad experiences with it causing tendon damage and severe back pain, though fortunately the damage healed and the back pain cleared within a couple days after stopping my Cipro course early and switching to a different antibiotic.

simonebrunozzi 4y ago

> As these were a significant contributor to my late wife's suicide. I can't even imagine how hard it is for you. I am sorry for your loss.

dml2135 4y ago

I personally experienced the negative affects of fluoroquinolone as well. I did a full course of Cipro and experienced horrible back pain, which was minimized by my doctor until he put me on Levaquin a few weeks later and I had to stop after a few days because the pain was so bad. Six years later I still have some lingering back pain from that incident, seems like it did at least some permanent damage. It was incredibly hard to deal with, on top of the chronic infection causing me to take the antibiotics in the first place. The most frustrating thing was the seeming indifference I got from many (not all) of the doctors I saw about it. Condolences for your loss, and my deepest sympathies.

aqme28 4y ago
Ugh Levaquin. One of the well-known side effects is a spontaneous Achilles tendon rupture. Horrifying, and I hated taking it.
- unethical_ban 4y ago
  That's a terrifying side effect.
  - Traubenfuchs 4y ago
    Don‘t forget about the chronic neuropathy! Some people have hands and feet that will burn and sting until their death. I had to take moxifloxacin and ciprofloxacin at two different times in my life. Besides the achilles, feet and hand tendon pain, both times I would have severe stinging pain in my scalp for months after taking them. Blessed as I am it went away again.

devwastaken 4y ago

The FDA warnings read like any other medication. This article does not point out why this is specifically worse, or how "rare" of an occurrence it is is or isn't. I can't know from this article wether the cause is this antibiotic.

antiatheist 4y ago

https://www.amr.gov.au/about-amr/amr-australia/amr-and-animal-health-australia https://www.amr.gov.au/about-amr/amr-australia/amr-and-anima...