3 ms·
There have been some wonderful advances in cancer therapy, such as immunotherapy. For example, Rituxan (rituximab) only dates to 1997, but it's already in a num
by msla 4y ago
There have been some wonderful advances in cancer therapy, such as immunotherapy. For example, Rituxan (rituximab) only dates to 1997, but it's already in a number of chemotherapy protocols, leading to a clear improvement in survival rates in previously difficult-to-treat cancers such as aggressive non-Hodgkin's lymphoma.
https://en.wikipedia.org/wiki/Rituximab https://en.wikipedia.org/wiki/Rituximab
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398399/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398399/
Flashier, and something I've already talked about, is CAR T-cell therapy, the first generations of which were approved in 2017. This therapy has definite risks of severe side-effects, but it can result in complete remission of cancers that have survived multiple lines of chemotherapy, as happened with me.
https://en.wikipedia.org/wiki/CAR_T_cell https://en.wikipedia.org/wiki/CAR_T_cell
Immunotherapy isn't just promising, it's here, and, because of it, so am I, but even more exciting is that it gives us more avenues of research to build off of known-useful therapies.
- Hackbraten 4y agoCongrats for your success!
- jorvi 4y ago> For example, Rituxan (rituximab) only dates to 1997 It is kind of scary to me that drugs these days have such long regulatory lead times that a drug developed in 1997 is just now being entered into treatment regimens. I understand why that is (the Thalidomide tragedy stuff and like that), but I also clearly remember reading an article ~10 years back that asked why cancer treatment seemingly hadn’t made any leapfrogs since the ~70s, and the answer was back then they could aggressively iterate on treatments.
- msla 4y agoI think you misunderstood: I said it dates to 1997 because that's when it was first approved for use in America. It's not that new in cancer therapy, with R-CHOP (the CHOP protocol plus Rituxan) apparently being introduced in the early 2000s: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036549/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036549/