The core finding in the article is: for 15% of people antidepressants provided large benefits independent of the placebo effect. What this suggests to me is th

The core finding in the article is: for 15% of people antidepressants provided large benefits independent of the placebo effect. What this suggests to me is the syndrome we call "depression" has multiple root causes, and current antidepressant medication treats at least one of them, but not all of them. Identifying those causes and finding ways to test for them could bring huge benefits, both in identifying people who would benefit from drugs, and avoiding unnecessary treatments for those who would not.