Not just manual filtering, there are many automatic/default filters like "KAM_INFOUSMEBIZ = Prevalent use of .info|.us|.me|.me.uk|.biz domains in spam/malware"

Not just manual filtering, there are many automatic/default filters like "KAM_INFOUSMEBIZ = Prevalent use of .info|.us|.me|.me.uk|.biz domains in spam/malware" It's not a guaranteed strike but I just had a look at the last email I had from a .biz and it got 0.8 added to it's spam score because it had a biz domain. Still got through as it was otherwise legit though.