It addresses different bioinformatic use cases, but plink2 is an open-source tool that is widely used and makes extensive use of zstd. In particular, it accept

It addresses different bioinformatic use cases, but plink2 is an open-source tool that is widely used and makes extensive use of zstd. In particular, it accepts both gzip- and zstd-compressed text files as input, but output commands that can generate large text files often only have a zstd compression option.