4 ms·
Visualizing the inside of cells at previously impossible resolutions
- maroonblazer 4y agovid Insights Into How They Work
- veilrap 4y agoFor a moment I thought this article was going to be about doing visualizations of cells using Vi(m)
- 7speter 4y agoStep away from the terminal emulator
- schemescape 4y agoAre there images somewhere in the article? All I saw was a title image (not sure if it is real or just an artistic interpretation), and a video (with a thumbnail that looked interesting, but apparently just a bunch of people talking).
- s1artibartfast 4y agoArticle: https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.13948 https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.1...
- hoseja 4y ago>Samples are rapidly frozen to protect them from radiation damage. Isn't this wrong? They are rapidly frozen so the water vitrifies and permits transmission of the electron beam. The samples still get damaged by the what is basically beta radiation.
- lordfrito 4y agoIf you're interested in seeing images generated by this technique, a google image search of "Cryo-Electron Tomography" came up with tons of hits. Here's a sample of articles with images [1] [2] [3] Wild stuff. I never would have guessed that we'd be able to image intact cell biology at this resolution in my lifetime. Excited for the possibilities for new discoveries opened up with all these new tools/methods. [1] https://www.thermofisher.com/blog/atomic-resolution/whats-possible-cryo-electron-tomography/ https://www.thermofisher.com/blog/atomic-resolution/whats-po... [2] https://www.biorxiv.org/content/10.1101/2021.07.28.454169v1.full https://www.biorxiv.org/content/10.1101/2021.07.28.454169v1.... [3] https://www.biochem.mpg.de/5268912/20160226_Mahamid_Baumeister https://www.biochem.mpg.de/5268912/20160226_Mahamid_Baumeist...