Using a custom dictionary works well if you want to compress single consensus sequences (30kbp), say before putting them into an sqlite db. Then you can get eac

Using a custom dictionary works well if you want to compress single consensus sequences (30kbp), say before putting them into an sqlite db. Then you can get each sequence down to ~200 bytes. If you compress a large dataset, there's no point in using a custom dictionary, the auto-embedded one works just fine.