Speaking as a chemo spouse, but it's the fatigue that's worst of all regarding work. The source of the fatigue differs depending on what drugs are involved - mi

Speaking as a chemo spouse, but it's the fatigue that's worst of all regarding work. The source of the fatigue differs depending on what drugs are involved - might be a mix of nausea/loss of appetite/brain-gut chaos, autoimmune, cardiovascular changes, sleep disruption, and/or nerve damage - but you'll feel miserably tired and it'll take time at best to adjust to the new cap on your energy. There's also chemo brain, which is easier(?) for people to consider lately since it sounds similar to long covid brain-fog. Your memory isn't as reliable, you think a little slower, you can't multitask as well as before, or at all. This also doesn't necessarily go away after treatment stops. If you need steroids to combat allergic reactions to chemo drugs, that adds even more emotional volatility. For my spouse, it was a wretched combo of chemo constipation/nausea/puking sapping them of sleep and fluids, anti-nausea meds exacerbating the chemo brain, and a prolonged initial treatment plan attempt involving steroids and a drug they were violently allergic to. They couldn't work through it.