5 ms·
It was concerning to see the mRNA vaccines associated with myocarditis. It seems like that made the public unnecessarily skeptical of mRNA as a technology. Bu
by alphazard 4y ago
It was concerning to see the mRNA vaccines associated with myocarditis. It seems like that made the public unnecessarily skeptical of mRNA as a technology. But my understanding is that was a protein engineering issue that could have happened with any vaccine technology and was not specific to mRNA as a platform.
Are there any experts here that can confirm that is a coincidence or explain why mRNA as a technology is more susceptible to issues like that?
- russdill 4y agoMyocarditis is a common immune reaction and not specific to mRNA or even vaccines https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786665/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786665/
- russdill 4y agoCommon is probably not the best word choice here.
- alphazard 4y agoThis is a case study of myocarditis after an influenza vaccine. This single data point, or even the fact that this is a possible immune reaction doesn't really speak to the issue I'm asking about. In the last few years a slew of COVID vaccines were widely deployed without myocarditis as a complication. The Pfizer and Moderna vaccines made headline news for their elevated risk of myocarditis, and resulted in changes in vaccine recommendations for certain demographics. Both were mRNA based. Do they have other things in common, dosage, proteins, preservatives, shelf lives? What else is similar between them and different from the other vaccines?