Comparing it to water or salt is such a low bar as to be meaningless. Acetaminophen toxicity starts at less than twice the recommended dose, which isn’t hard to

Comparing it to water or salt is such a low bar as to be meaningless. Acetaminophen toxicity starts at less than twice the recommended dose, which isn’t hard to achieve if someone doesn’t read the guidelines (we generally expect otc medicines to be safe) or if they’re mixing drugs. And that’s for a healthy liver that’s not further burdened with alcohol or other hepatotoxic medicines.