Long term for web apps is JavaScript and REST because it gives you a common service back end for mobile and other consumers of your services. Take a look at Req

Long term for web apps is JavaScript and REST because it gives you a common service back end for mobile and other consumers of your services. Take a look at Require.js, Backbone.js and jQuery build a webapp with them that communicates with some REST services. For content based sites, the Python web projects are coming on strong and ROR has a lot of mind-share.