> But at a population level, we know definitively that "grind it out with exercise, nutrition, and therapy" is not an effective public health strategy. I'm pre

> But at a population level, we know definitively that "grind it out with exercise, nutrition, and therapy" is not an effective public health strategy. I'm pretty sure most people skip the therapy. Maybe that's the problem. Changing your relationship with your lifestyle and your food involves a commitment to changing yourself. Were I in that position, I'd be more inclined to try psychedelics to change how I think than I would new drugs that mess with metabolism. Another tack we could take is to change the available food options and tax the hell out of problematic foods and heavily subsidize healthier foods. That's a population-level policy that will almost certainly have long term population level effects. > If these drugs continue to prove safe That's just it, long-term effects aren't known.