GLP-1 agonists are an incredibly effective pharmaceutical intervention, why are you dismissive of them? behavorial interventions for weight loss don't work cli

GLP-1 agonists are an incredibly effective pharmaceutical intervention, why are you dismissive of them? behavorial interventions for weight loss don't work clinically. the only other intervention that comes close to the effect size of GLP-1 agonists is surgery. you can argue that they treat the symptoms and not the disease, sure. the mechanisms of systemic obesity aren't well understood. but it's inarguable that this is disease of homeostatic misregulation, the set point is too high. which is why behavioral interventions fail. we don't talk down to the people suffering from other diseases of homeostatic misregulation (eg diabetes) for their moral failings, we treat it. but that's how diabetes is treated now, "just stop being fat". It is very much in analogous to where depression was 30 years ago. Now, therapy and anti-depressants are widespread and destigmatized. The difference is that while SSRIs are only marginally better than placebo, GLP-1 agonists are _incredibly_ effective. Huge effect sizes. I think in 30 years you're going to look back on your opinions now and be embarrassed that you were telling people to avoid a very effective and safe pharmaceutical intervention and "just stop being depressed" I've been having the same conversation over and over again since GLP-1 agonists were approved and it's always the same. People who are opposed to a very effective pharmaceutical intervention but are not able to articulate any cogent reason as to why. It's just stigma.