7 ms·

> It’s so hard to eat healthy, I honestly cannot fathom how people do it. When I started taking semaglutide, I finally understood it. I'd eat a salad... and be

> It’s so hard to eat healthy, I honestly cannot fathom how people do it. When I started taking semaglutide, I finally understood it. I'd eat a salad... and be full and more than satisfied! I'd look at a muffin right after lunch, and go "eh, better things to do with my time" instead of immediately having an overriding desire to eat eat eat. Before, I could eat half a pizza and still be hungry (way out of what my body needs); now, a slice is more than sufficient and satiety lasts well into the next morning. GLP-1 agonists makes eating healthy trivial and automatic, instead of a dieting state where you're thinking about food literally constantly throughout the day for months or years on end. Too many people are convinced that everyone has the same subjective experiences of hunger and craving, but it's simply not the case. Some people implicitly hold this idea because it's a convenient ideology that allows people to morally congratulate themselves for having a functioning satiety circuit.

rubicon33 4y ago
> Too many people are convinced that everyone has the same subjective experiences of hunger and craving, but it's simply not the case. Some people implicitly hold this idea because it's a convenient ideology that allows people to morally congratulate themselves for having a functioning satiety circuit. Where does this line of thinking stop? Is everything pre-determined by genetics? Is everyone who is smarter than me, just actually lucky that their dopamine system works correctly, and mine doesn't, and hasn't since I was a very young kid? I'm sure this response will get down voted but its an honest question. This line of thinking that everything is genetically pre-determined seems both accurate and somewhat depressing. It means that if I'm skinny and can't gain weight, I need to take steroids and lift. Or if I'm fat, I should take a GLP-1 agonist. If I'm underperforming in my career or school, I should take adderal or similar pharma solutions. What role does good old fashioned hard work and discipline have in this day and age?
- tormeh 4y ago
  We’re products of our nature and environment. Belief in free will, virtue, etc. are useful beliefs, but they’re also just not true.
  - raspberry1337 4y ago
    Free will is a product of our nature.
- nunez 4y ago
  I don't think _everything_ comes down to genetics, but a lot of stuff does, including the attributes you mentioned here.
- scarmig 4y ago
  I didn't say anything about genetics, though I wouldn't be surprised if that plays a part. Might be how you were raised. Might be simply your cumulative life path leaving you in a particular state. Might be toxins in the environment. It doesn't matter; in the existing present, people have wildly different responses to food and diet. As for your actual question, it depends on the particular thing we're talking about. For obesity, we've tried telling people to do more hard work and discipline, and it's been a spectacular failure. Plenty of people who do work hard and have incredible discipline in other areas of their life fail when it comes to getting to a normal BMI. There are large subjectivities involved, but when I got down to a 22 BMI at one point via the hard work and discipline route, I was constantly overwhelmed with thoughts of food, literally every waking second; this was despite trying and adhering to probably a half dozen different diets. Most people able to maintain a constant 22 BMI don't experience this. This also is more common in our current society, for whatever reason (likely not genes, since we're close enough to our grandparents), than it was historically. This isn't some natural state of affairs we live in. So, bring on the drugs! If there are ones that help other things with minimal side effects, bring them on too. Everyone wins, because we end up with a better, happier, more productive society.
  - depressedpanda 4y ago
    > There are large subjectivities involved, but when I got down to a 22 BMI at one point via the hard work and discipline route, I was constantly overwhelmed with thoughts of food, literally every waking second; this was despite trying and adhering to probably a half dozen different diets. Most people able to maintain a constant 22 BMI don't experience this. Out of curiosity, what kind of food were you obsessing over, specifically? Why were you craving that kind of food, instead of, say, lettuce?
    - scarmig 4y ago
      For me, it was primarily carbs. Not potato chips or anything particularly greasy, but things like tortillas, rice, noodles, bread, potatoes. As to why, who knows. I'd be "starving" but have zero desire to eat lettuce, but then jump on the first chance I got to eat a couple cups of rice.
- nerdbert 4y ago
  Let's say there were a drug that made people motivated to study hard and get a lot of work done. Would the successes people reaped from that be less useful to themselves and people around them, than those which other people reaped from being natively predisposed in that direction?
- hypatiadotca 4y ago
  If your eyes got bad, would you get glasses? My brain doesn't produce the same amount of dopamine as a non-ADHD human's brain. It's morally neutral to fix that with medication, same as it's morally neutral to wear glasses, imo.
- telchior 4y ago
  Instead of thinking in terms of "everything", "everyone", etc, it may help to think in terms of bell curves and outliers on that curve. Would you be willing to believe that, out of 7+ billions people in the world, there is at least one person whose brain is set up to constantly hammer them with feelings of hunger? (I'm not sure how a basic proposition like this could be rejected, since the chemicals and processes that govern hunger are something that science actually has some understanding of, and we also know that basically anything can go haywire.) Next: if you can believe that one person is such an outlier, can you believe that hundreds are? Thousands? Millions? Whatever size that group is, it seems like a possible answer to your worry of when these lines of thinking stop. Perhaps some outlying group of people do actually need something more than "good old fashioned hard work and discipline", especially considering that thousands of years of people repeating such sentiments hasn't solved quite a lot of problems (beyond just obesity).
  - naasking 4y ago
    > Next: if you can believe that one person is such an outlier, can you believe that hundreds are? Thousands? Millions? Yes, those people exist as outliers. But a population-level outlier theory doesn't explain why obesity is growing in the population.
    - scrollaway 4y ago
      ADHD used to be only a tiny amount of outliers and is growing, thanks to the lifestyle we lead. Obesity is similar. This feeling of hunger is thrown out of whack often not by genetic but by lifestyle. I’m lucky enough that I haven’t felt it all my life, but I have felt it during multiple phases of my life; i know exactly how eating the wrong kinds of food can teach your body to eat more than it needs and to adapt to that new number. Our environment sucks ass.
      - chownie 4y ago
        > ADHD used to be only a tiny amount of outliers and is growing, thanks to the lifestyle we lead. I think this might be a misunderstanding. Rates of ADHD may be higher but I think it's more likely we have an environment which now challenges people with ADHD more than in the past. The advent of electrical lighting did not cause an increase in pattern-reactive epilepsy, it just created conditions in which pattern-reactive epilepsy were more likely to be triggered. I believe now is the same.
- derefr 4y ago
  "Hard work and discipline" are multipliers for the output of an otherwise-balanced brain and body chemistry. But they're no substitute for fixing that balance when it is imbalanced. An analogy: "hard work" is what your car's engine does when you throttle it up. But that "hard work" isn't going to take you very far — or even in the right direction — if the car's wheels aren't aligned and balanced equidistantly on the car's axle. This "imbalance" will mean that any power put into the system, just gets shunted into running you faster and faster in circles, and/or into "spinning your wheels" and "burning out." Bringing the car into balance is an overriding concern. You won't get anywhere without first doing that, no matter how hard you push the engine. Once you've done that, though, then the amount of power you're pushing through the engine — your "hard work and discipline" – becomes relevant.
- not_kurt_godel 4y ago
  Why are you more worried about "good old fashioned hard work and discipline" than taking a scientific and results-oriented approach to improve people's lives? Do you want to see people toil and suffer for its own sake?
  - ithkuil 4y ago
    Funnily enough one could argue that we're also biologically predisposed to apply certain moral judgements to the behaviour of other people and our own. After all, our environment of selection didn't include the ability to alter much of our body chemistry.
- Gwarzo 4y ago
  [flagged]
  - dang 4y ago
    You're breaking the site guidelines badly with your posts in this thread. Moreover it looks like you've done that more than once in the past as well. Can you please stop? It's not what this site is for, and destroys what it is for. We want curious conversation, not angry putdowns. If you wouldn't mind reviewing https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html and taking the intended spirit of the site more to heart, we'd be grateful.
- concordDance 4y ago
  Genetics and microbiome are the biggest factors, but training, habits and environment (how accessible is that junk food?) also matters.
- tomp 4y ago
  There is 0% chance that human genetics changed this much in the last 100 years (3-4 generations). Look at photos from 100 years ago, people were mostly thin. So no, we’re not genetically predetermined to be hungry. There’s something in our environment that’s messing with our circuits. Either some toxins (e.g. endocrine disrupters) or hyper palatable food (artificially engineered for max enjoyment and min satiety), or maybe something else.
  - BuyMyBitcoins 4y ago
    But this doesn’t dismiss the idea that some people are genetically predisposed to be far hungrier. While true cheap and abundant calories facilitate obesity, that probably synergizes with people who have naturally voracious appetites. Someone in the pre-industrialized past wouldn’t have been able to binge on so much calorie dense food, but they may very well have felt gnawing hunger more strongly than their peers.
- pmarreck 4y ago
  > Is everything pre-determined by genetics? Well, much more is, than isn't, it seems. You may trim the sails, but life will provide you your wind direction... And in this case: "As many as 400 genes have been shown to affect body weight in one way or another." https://www.genomicseducation.hee.nhs.uk/blog/obesity-is-it-in-our-genes/ https://www.genomicseducation.hee.nhs.uk/blog/obesity-is-it-...
tdeck 4y ago
> Too many people are convinced that everyone has the same subjective experiences of hunger and craving, but it's simply not the case. Some people implicitly hold this idea because it's a convenient ideology that allows people to morally congratulate themselves for having a functioning satiety circuit. As someone who's always been thin and doesn't have a strong appetite, I couldn't agree more. I'm just enough outside the norm yo be able to recognize it. There are times when I simply can't force myself to finish my food and it goes to waste, but the upside is that many people assume that people in my body fat range are somehow virtuous for not "overeating". That's not the case at all - I don't eat particularly healthy, don't have any particular exercise routine beyond walking, and I don't limit myself. I just get full quickly and have a metabolism that burns what I eat.
- scarmig 4y ago
  I applaud that self knowledge. It's always hard to know others' experiences. I have a friend who genuinely tried to help me lose weight in college with the typical advice and a lot of support: he had the strategy of just eating until he was full and then stopping, and he just couldn't get why that didn't work for me. But when he hit his 30s, he suddenly started ballooning up and suddenly couldn't put his strategy into practice, to his great frustration. Did his willpower dry up overnight? Nope; something else changed to upregulate his appetite. (I pointed him to semaglutide, and he's already halfway to returning to his college weight.)
- wnolens 4y ago
  I'm in a similar boat as you. COMPLETE opposite experience as other folks, to the point of pathology. I could not overeat to save my life. I cannot lift weights and expect any growth due to lack of caloric intake. When I try to exceed 2k calories in a day, I find myself so full I need to lie down and groan for an hour until things move and digest. Force any more down and I'll vomit. I cannot concentrate with a meal in my stomach, so I wake at 9, eat ~500cal at 1pm, and leave the rest til I'm done work at 8. Sometimes I lose 15lbs when having a bout of constipation due to goddamn IBS. Every person in my life, friend or foe or family or partner finds it clever and completely acceptable to tell me I'm "too skinny and need to eat more". Others without my experience just don't get it. Glad these overweight folks have a tool to help them.
Auracle 4y ago
I'm sorry, but I'm a decently in shape person that tried semaglutide for reasons other than losing weight and I disagree. While I'm sure we all are a bit different satiety wise (and I've found it greatly depends on how much I've been eating overall recently), your experience on the drug is not what the rest of us feel like all the time. It's unfortunately normal for our biology to basically want to shove calories down our mouths all the time. I consciously pace my food intake every single day. I just had a huge plate of nachos, some christmas cookies, and a pickle...and I could still eat more. The only reason I ate that much is because I feel a cold coming on so I relaxed my usual limits. The kind of "fullness" you get on semaglutide isn't natural. I've never felt like that my entire life. The closest thing would be after something like a Thanksgiving meal, but that's more of a "my stomach hurts" than "I really don't feel like I can put more in my stomach." My sister in law is the skinniest, most in shape person I know. She's 35, has had 3 kids, and has abs, an ass she clearly worked for, etc. My wife (unfortunately) regularly compares herself to her and in this case also thinks like you, that it just comes naturally. She gave me her old phone so I could test some stuff on it as I don't have an Android phone handy. She didn't wipe it. MyFitnessPal was on there, and she was limiting herself to 1400 calories a day. Almost all of us work for it. Truth be told, and please hold your downvotes for this, I get a little upset when the rest of you get to have insurance pay ridiculous sums of money for a medication that makes it easier for you than the rest of us, side effects aside, and you think it's simply evening out the playing field. And it needs to be said in case my wife ever finds this: she's also ridiculously hot and even though she can't see it has, at times, been skinnier than her sister.
- Blackthorn 4y ago
  > I get a little upset when the rest of you get to have insurance pay ridiculous sums of money for a medication If this was well and truly about the money you'd support it, because it's going to be cheaper than paying for long-term medical costs of obesity.
  - Auracle 4y ago
    Yeah, and that's a definite bonus. It's the attitude I've read from people taking it that grinds my gears - when I read the semaglutide subreddit it was full of people saying "oh, so this is what skinny people feel like." No, how you feel on the drug isn't how most of us skinny people feel. I'm probably somewhat uniquely qualified to make that distinction at the moment. The rest of us have worked hard our entire lives to stay skinny and now you all get a cheat. It's one thing if you recognize it, but it's beyond annoying if you don't.

rubicon33 4y ago

> Too many people are convinced that everyone has the same subjective experiences of hunger and craving, but it's simply not the case. Some people implicitly hold this idea because it's a convenient ideology that allows people to morally congratulate themselves for having a functioning satiety circuit. Where does this line of thinking stop? Is everything pre-determined by genetics? Is everyone who is smarter than me, just actually lucky that their dopamine system works correctly, and mine doesn't, and hasn't since I was a very young kid? I'm sure this response will get down voted but its an honest question. This line of thinking that everything is genetically pre-determined seems both accurate and somewhat depressing. It means that if I'm skinny and can't gain weight, I need to take steroids and lift. Or if I'm fat, I should take a GLP-1 agonist. If I'm underperforming in my career or school, I should take adderal or similar pharma solutions. What role does good old fashioned hard work and discipline have in this day and age?

tormeh 4y ago
We’re products of our nature and environment. Belief in free will, virtue, etc. are useful beliefs, but they’re also just not true.
- raspberry1337 4y ago
  Free will is a product of our nature.
nunez 4y ago
I don't think _everything_ comes down to genetics, but a lot of stuff does, including the attributes you mentioned here.
scarmig 4y ago
I didn't say anything about genetics, though I wouldn't be surprised if that plays a part. Might be how you were raised. Might be simply your cumulative life path leaving you in a particular state. Might be toxins in the environment. It doesn't matter; in the existing present, people have wildly different responses to food and diet. As for your actual question, it depends on the particular thing we're talking about. For obesity, we've tried telling people to do more hard work and discipline, and it's been a spectacular failure. Plenty of people who do work hard and have incredible discipline in other areas of their life fail when it comes to getting to a normal BMI. There are large subjectivities involved, but when I got down to a 22 BMI at one point via the hard work and discipline route, I was constantly overwhelmed with thoughts of food, literally every waking second; this was despite trying and adhering to probably a half dozen different diets. Most people able to maintain a constant 22 BMI don't experience this. This also is more common in our current society, for whatever reason (likely not genes, since we're close enough to our grandparents), than it was historically. This isn't some natural state of affairs we live in. So, bring on the drugs! If there are ones that help other things with minimal side effects, bring them on too. Everyone wins, because we end up with a better, happier, more productive society.
- depressedpanda 4y ago
  > There are large subjectivities involved, but when I got down to a 22 BMI at one point via the hard work and discipline route, I was constantly overwhelmed with thoughts of food, literally every waking second; this was despite trying and adhering to probably a half dozen different diets. Most people able to maintain a constant 22 BMI don't experience this. Out of curiosity, what kind of food were you obsessing over, specifically? Why were you craving that kind of food, instead of, say, lettuce?
  - scarmig 4y ago
    For me, it was primarily carbs. Not potato chips or anything particularly greasy, but things like tortillas, rice, noodles, bread, potatoes. As to why, who knows. I'd be "starving" but have zero desire to eat lettuce, but then jump on the first chance I got to eat a couple cups of rice.
nerdbert 4y ago
Let's say there were a drug that made people motivated to study hard and get a lot of work done. Would the successes people reaped from that be less useful to themselves and people around them, than those which other people reaped from being natively predisposed in that direction?
hypatiadotca 4y ago
If your eyes got bad, would you get glasses? My brain doesn't produce the same amount of dopamine as a non-ADHD human's brain. It's morally neutral to fix that with medication, same as it's morally neutral to wear glasses, imo.
telchior 4y ago
Instead of thinking in terms of "everything", "everyone", etc, it may help to think in terms of bell curves and outliers on that curve. Would you be willing to believe that, out of 7+ billions people in the world, there is at least one person whose brain is set up to constantly hammer them with feelings of hunger? (I'm not sure how a basic proposition like this could be rejected, since the chemicals and processes that govern hunger are something that science actually has some understanding of, and we also know that basically anything can go haywire.) Next: if you can believe that one person is such an outlier, can you believe that hundreds are? Thousands? Millions? Whatever size that group is, it seems like a possible answer to your worry of when these lines of thinking stop. Perhaps some outlying group of people do actually need something more than "good old fashioned hard work and discipline", especially considering that thousands of years of people repeating such sentiments hasn't solved quite a lot of problems (beyond just obesity).
- naasking 4y ago
  > Next: if you can believe that one person is such an outlier, can you believe that hundreds are? Thousands? Millions? Yes, those people exist as outliers. But a population-level outlier theory doesn't explain why obesity is growing in the population.
  - scrollaway 4y ago
    ADHD used to be only a tiny amount of outliers and is growing, thanks to the lifestyle we lead. Obesity is similar. This feeling of hunger is thrown out of whack often not by genetic but by lifestyle. I’m lucky enough that I haven’t felt it all my life, but I have felt it during multiple phases of my life; i know exactly how eating the wrong kinds of food can teach your body to eat more than it needs and to adapt to that new number. Our environment sucks ass.
    - chownie 4y ago
      > ADHD used to be only a tiny amount of outliers and is growing, thanks to the lifestyle we lead. I think this might be a misunderstanding. Rates of ADHD may be higher but I think it's more likely we have an environment which now challenges people with ADHD more than in the past. The advent of electrical lighting did not cause an increase in pattern-reactive epilepsy, it just created conditions in which pattern-reactive epilepsy were more likely to be triggered. I believe now is the same.
derefr 4y ago
"Hard work and discipline" are multipliers for the output of an otherwise-balanced brain and body chemistry. But they're no substitute for fixing that balance when it is imbalanced. An analogy: "hard work" is what your car's engine does when you throttle it up. But that "hard work" isn't going to take you very far — or even in the right direction — if the car's wheels aren't aligned and balanced equidistantly on the car's axle. This "imbalance" will mean that any power put into the system, just gets shunted into running you faster and faster in circles, and/or into "spinning your wheels" and "burning out." Bringing the car into balance is an overriding concern. You won't get anywhere without first doing that, no matter how hard you push the engine. Once you've done that, though, then the amount of power you're pushing through the engine — your "hard work and discipline" – becomes relevant.
not_kurt_godel 4y ago
Why are you more worried about "good old fashioned hard work and discipline" than taking a scientific and results-oriented approach to improve people's lives? Do you want to see people toil and suffer for its own sake?
- ithkuil 4y ago
  Funnily enough one could argue that we're also biologically predisposed to apply certain moral judgements to the behaviour of other people and our own. After all, our environment of selection didn't include the ability to alter much of our body chemistry.
Gwarzo 4y ago
[flagged]
- dang 4y ago
  You're breaking the site guidelines badly with your posts in this thread. Moreover it looks like you've done that more than once in the past as well. Can you please stop? It's not what this site is for, and destroys what it is for. We want curious conversation, not angry putdowns. If you wouldn't mind reviewing https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html and taking the intended spirit of the site more to heart, we'd be grateful.
concordDance 4y ago
Genetics and microbiome are the biggest factors, but training, habits and environment (how accessible is that junk food?) also matters.
tomp 4y ago
There is 0% chance that human genetics changed this much in the last 100 years (3-4 generations). Look at photos from 100 years ago, people were mostly thin. So no, we’re not genetically predetermined to be hungry. There’s something in our environment that’s messing with our circuits. Either some toxins (e.g. endocrine disrupters) or hyper palatable food (artificially engineered for max enjoyment and min satiety), or maybe something else.
- BuyMyBitcoins 4y ago
  But this doesn’t dismiss the idea that some people are genetically predisposed to be far hungrier. While true cheap and abundant calories facilitate obesity, that probably synergizes with people who have naturally voracious appetites. Someone in the pre-industrialized past wouldn’t have been able to binge on so much calorie dense food, but they may very well have felt gnawing hunger more strongly than their peers.
pmarreck 4y ago
> Is everything pre-determined by genetics? Well, much more is, than isn't, it seems. You may trim the sails, but life will provide you your wind direction... And in this case: "As many as 400 genes have been shown to affect body weight in one way or another." https://www.genomicseducation.hee.nhs.uk/blog/obesity-is-it-in-our-genes/ https://www.genomicseducation.hee.nhs.uk/blog/obesity-is-it-...

tdeck 4y ago

> Too many people are convinced that everyone has the same subjective experiences of hunger and craving, but it's simply not the case. Some people implicitly hold this idea because it's a convenient ideology that allows people to morally congratulate themselves for having a functioning satiety circuit. As someone who's always been thin and doesn't have a strong appetite, I couldn't agree more. I'm just enough outside the norm yo be able to recognize it. There are times when I simply can't force myself to finish my food and it goes to waste, but the upside is that many people assume that people in my body fat range are somehow virtuous for not "overeating". That's not the case at all - I don't eat particularly healthy, don't have any particular exercise routine beyond walking, and I don't limit myself. I just get full quickly and have a metabolism that burns what I eat.

scarmig 4y ago
I applaud that self knowledge. It's always hard to know others' experiences. I have a friend who genuinely tried to help me lose weight in college with the typical advice and a lot of support: he had the strategy of just eating until he was full and then stopping, and he just couldn't get why that didn't work for me. But when he hit his 30s, he suddenly started ballooning up and suddenly couldn't put his strategy into practice, to his great frustration. Did his willpower dry up overnight? Nope; something else changed to upregulate his appetite. (I pointed him to semaglutide, and he's already halfway to returning to his college weight.)
wnolens 4y ago
I'm in a similar boat as you. COMPLETE opposite experience as other folks, to the point of pathology. I could not overeat to save my life. I cannot lift weights and expect any growth due to lack of caloric intake. When I try to exceed 2k calories in a day, I find myself so full I need to lie down and groan for an hour until things move and digest. Force any more down and I'll vomit. I cannot concentrate with a meal in my stomach, so I wake at 9, eat ~500cal at 1pm, and leave the rest til I'm done work at 8. Sometimes I lose 15lbs when having a bout of constipation due to goddamn IBS. Every person in my life, friend or foe or family or partner finds it clever and completely acceptable to tell me I'm "too skinny and need to eat more". Others without my experience just don't get it. Glad these overweight folks have a tool to help them.

Auracle 4y ago

I'm sorry, but I'm a decently in shape person that tried semaglutide for reasons other than losing weight and I disagree. While I'm sure we all are a bit different satiety wise (and I've found it greatly depends on how much I've been eating overall recently), your experience on the drug is not what the rest of us feel like all the time. It's unfortunately normal for our biology to basically want to shove calories down our mouths all the time. I consciously pace my food intake every single day. I just had a huge plate of nachos, some christmas cookies, and a pickle...and I could still eat more. The only reason I ate that much is because I feel a cold coming on so I relaxed my usual limits. The kind of "fullness" you get on semaglutide isn't natural. I've never felt like that my entire life. The closest thing would be after something like a Thanksgiving meal, but that's more of a "my stomach hurts" than "I really don't feel like I can put more in my stomach." My sister in law is the skinniest, most in shape person I know. She's 35, has had 3 kids, and has abs, an ass she clearly worked for, etc. My wife (unfortunately) regularly compares herself to her and in this case also thinks like you, that it just comes naturally. She gave me her old phone so I could test some stuff on it as I don't have an Android phone handy. She didn't wipe it. MyFitnessPal was on there, and she was limiting herself to 1400 calories a day. Almost all of us work for it. Truth be told, and please hold your downvotes for this, I get a little upset when the rest of you get to have insurance pay ridiculous sums of money for a medication that makes it easier for you than the rest of us, side effects aside, and you think it's simply evening out the playing field. And it needs to be said in case my wife ever finds this: she's also ridiculously hot and even though she can't see it has, at times, been skinnier than her sister.

Blackthorn 4y ago
> I get a little upset when the rest of you get to have insurance pay ridiculous sums of money for a medication If this was well and truly about the money you'd support it, because it's going to be cheaper than paying for long-term medical costs of obesity.
- Auracle 4y ago
  Yeah, and that's a definite bonus. It's the attitude I've read from people taking it that grinds my gears - when I read the semaglutide subreddit it was full of people saying "oh, so this is what skinny people feel like." No, how you feel on the drug isn't how most of us skinny people feel. I'm probably somewhat uniquely qualified to make that distinction at the moment. The rest of us have worked hard our entire lives to stay skinny and now you all get a cheat. It's one thing if you recognize it, but it's beyond annoying if you don't.