3 ms·
> these drugs are like a supercharged metformin No drinking alcohol, like metformin? If so, I suspect you could get a large fraction of the improvement gained
by yamtaddle 4y ago
> these drugs are like a supercharged metformin
No drinking alcohol, like metformin?
If so, I suspect you could get a large fraction of the improvement gained from a population-wide deployment of these drugs, at zero cost, if everyone just stopped drinking alcohol. "But that's unreasonable!" Right, so if that's also required for taking this drug, then....
- rayiner 4y agoMy whole family mostly avoids alcohol (Muslim) and lots of people are overweight.
- 1024core 4y agoIt's the sugars that get you. Avoid processed foods at all cost. And avoid simple carbs like white bread, white rice, etc.
- selimthegrim 4y agoAsking a Bengali to avoid white rice is going to get you laughed out of the room.
- rayiner 4y agoMy parents keep rice in a 20 gallon metal bucket and it’s just the two of them. It’s gotta hold 100+ pounds of rice.
- 1024core 4y agoYou can always switch to brown rice. It's not the same, but over time you get used to it.
- selimthegrim 4y agoIt has some anti nutrient properties with iron and/or calcium (phytic acid?)
- happyopossum 4y ago> No drinking alcohol, like metformin? I take Metformin (not for diabetes, but weight and age) and my doc has never said a word about alcohol. A quick google suggests the possible bad interactions are diabetes related, so probably not applicable.
- yamtaddle 4y agoOh, interesting. I guess the cases I know of its use are diabetes related, now that I think about it, but I'd seen "I take metformin, so no alcohol" enough times I thought it was a drug interaction.
- alexfoo 4y agoAre you thinking of metronidazole? It’s listed as an example of a drug that has the “disulfiram effect” when mixed with alcohol. See the “Similarly acting substances” section of https://en.m.wikipedia.org/wiki/Disulfiram https://en.m.wikipedia.org/wiki/Disulfiram