Subtly different subjects to those two sentences: the former is talking about the new generation of medications (i.e. the general concept of medications targeti

Subtly different subjects to those two sentences: the former is talking about the new generation of medications (i.e. the general concept of medications targeting this new receptor); while the latter is talking about one specific treatment (i.e. one specific medication, at one specific dosage, via one specific route of administration, at one specific interval.) The side-effects of this particular treatment "can be severe", but that doesn't imply anything about the side-effects of any other treatment (combination of medication, dose, RoA, and interval) for drugs in this class. Heck, they could probably fix the nausea/vomiting just by making a pill that contains an adjunct anti-emetic like ondansetron, like they do for cancer drugs.