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Can't we already do this with CRISPR ? > The earlier proteins may be able to do things that the current CRISPRs cannot, such as cutting both double and single-
by bilekas 4y ago
Can't we already do this with CRISPR ?
> The earlier proteins may be able to do things that the current CRISPRs cannot, such as cutting both double and single-stranded DNA and RNA sequences at the same time.
To my uninformed reading, this seems less predictable, maybe more potent/capable but if I'm slicing DNA, I want as few unknowns as possible?
Super cool research, but like so many of these articles I don't see any real world impact for a few generations at least.
- etiam 4y agoThe impact is definitely here already. I found it slightly absurd to read the motivation ”this work is important, because it opens up a huge toolbox for creating better CRISPR systems.” considering CRISPR as biotechnology was still a marginally known frontline research tool at the start of the previous decade. Now it's ubiquitous to the point of being viewed as almost indispensible. The really interesting motivation to me though, is the other one: “Thanks to this recovery, we can see how the immune system of microbes became less harmful to its carriers and increasingly specific for each virus.”