In principle, load-store architectures are simpler to implement, simpler to write compilers for, simpler to write speculative optimizations for, and have denser

In principle, load-store architectures are simpler to implement, simpler to write compilers for, simpler to write speculative optimizations for, and have denser/simpler instruction encodings. Similarly in principle, register-memory architectures are simpler to write assembly for as a human, and simpler to write different speculative optimizations for.