K-holing can be a horrid idea on a home-dose of Ketamine due to the death spiral of tolerance that ensues. That's what causes the feedback loop of psychological

K-holing can be a horrid idea on a home-dose of Ketamine due to the death spiral of tolerance that ensues. That's what causes the feedback loop of psychological addiction that brings some of the opioid addiction-like horror to the table for this particular treatment, and one of the things I think that could be used to (wrongly, and unethically by some potentially unscrupulous lawmakers of any political dimension) shut it down in the future if too many people began abusing that.