I'm personally leaning towards the viral theory I've seen some research about. The general idea is that the brain produces these products as a defense to one of

I'm personally leaning towards the viral theory I've seen some research about. The general idea is that the brain produces these products as a defense to one of several viruses as a self defense mechanism but that those proteins may do bad things as well. Apparently population studies of people who take antiviral medications for herpes showed a significant decline in incidences of Alzheimer's. I haven't followed it closely lately so I am not sure if that is a return to baseline from an elevated risk (e.x. say that herpes increases baseline risk and treatment restores it) or if it might be generally applicable. Given that most drugs that have targeted Amyloid have failed to produce results so far, something like the Tau hypothesis or viral infection seem to me to be possibilities. Again, I haven't kept up lately so I would be happy to be "corrected" with some new things to read up on.