Consider me highly skeptical of any AI models predicting biology. The way these models were is more or less by association. There is no foundational understand

Consider me highly skeptical of any AI models predicting biology. The way these models were is more or less by association. There is no foundational understanding of underlying pathways or likely decomposition products. The AI models can be used as a first stage filter: generate a bunch of putative products computationally, filter them through predicted toxicity profile, and then start real testing (though you are likely leaving out solid leads from false positives). AI can be a human assisting tool, but it is in no way sufficient for leap-frogging into human testing.