I don't think you re-patent an off-label use, you re-patent a minor modification. See for example ketamine to eskatamine; or citalopram to escitalopram. Once y

I don't think you re-patent an off-label use, you re-patent a minor modification. See for example ketamine to eskatamine; or citalopram to escitalopram. Once you have the new med you use the courts to prevent the off-label use. See eg lucentis or avastin for Wet AMD.