I've only used numba once but I was really impressed. We have an analysis at work that runs hundreds of times a day which uses a Hampel filter written in numpy,

I've only used numba once but I was really impressed. We have an analysis at work that runs hundreds of times a day which uses a Hampel filter written in numpy, but still requires iterating over an array. Just adding a @numba.jit decorator above the function gave us a 10x speed improvement.