Also 40 years ago, 40-some years after penicillin was introduced, gonorrhea had evolved to produce an enzyme that acted specifically against it, penicillinase.

Also 40 years ago, 40-some years after penicillin was introduced, gonorrhea had evolved to produce an enzyme that acted specifically against it, penicillinase. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1046026/pdf/brjvendis00014-0062.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1046026/pdf/brj... No matter how many new, different, or even radical antibiotics we develop, unless we get ahead of over-prescribing and under-treating (not taking all of a prescribed treatment course) we will continue to rapidly evolve more successful micro-organisms, to our own detriment.