4 ms·
Also not a geneticist, but I'm pretty sure this is wrong because you only get recombination between analogous autosome pairs. The allosomes, or sex chromosomes,
by nonameiguess 4y ago
Also not a geneticist, but I'm pretty sure this is wrong because you only get recombination between analogous autosome pairs. The allosomes, or sex chromosomes, you just get from one parent anyway. Females get the X from the mother and the X from the father, but rather than recombination producing an X that is different from either parent, one of them just gets deactivated randomly in every cell during embryonic development and the offspring ends up with a single active X in each cell, usually roughly 50/50 split between exactly the same as the father and exactly the same as the mother. This is true in placental mammals, but in marsupials, it is always the father's X that gets deactivated.
So it seems like making XX from a single XY person would just end up doing something genetically similar to what already happens with marsupials, which doesn't result in non-viability.
Of course, cloning at all does result in not getting genetic diversity you would normally get from recombination, which can eventually result in population-level problems if you're doing enough of it.
- adrian_b 4y agoThe recombination happens when the gametes are produced, during meiosis. While in males there is no recombination between the X and Y chromosomes, in females sometimes there is recombination between the two X chromosomes. Therefore the X chromosome received by a child from the mother may either be 1 of the 2 X chromosomes of the mother, chosen randomly, or it may be a combination of those 2 X chromosomes. The inactivation of an X chromosome happens only in the female somatic cells, where the remaining active X chromosome is either the X chromosome of the father or 1 of the 2 X chromosomes of the mother or a combination of the 2 X chromosomes of the mother.