Wasm doesn't need to be interpreted, it's designed to be compatible with streaming compilers to produce machine code as the file is being downloaded, which can

Wasm doesn't need to be interpreted, it's designed to be compatible with streaming compilers to produce machine code as the file is being downloaded, which can then be optimised more completely later on. In a Docker-like situation, I would imagine that you can skip the first compilation step altogether and just generate optimised code. I suspect that still won't be as optimal as if you'd compiled the application for the target architecture in the first place, but I would suspect for most applications the performance will be relatively negligible.