Probably one of the main differences would be due to re-digesting the MIDI back into sound. I think Zenph's tech actually plays the piano and physically records

Probably one of the main differences would be due to re-digesting the MIDI back into sound. I think Zenph's tech actually plays the piano and physically records it. For MIDI, you'd probably use samplers like NI's Kontakt, and while the huge amount of collections available on that platform definitely are closer to real-world sound and variability, if you're just bouncing the raw to audio without re-recording in a physical space, there's probably at least some number of people who could tell the difference. I think there are physical modeling-based VSTs and instruments available, but it's been a really long time since I looked into that space. The biggest difference is that I'm sure if you introduced Gould to the world of MIDI and DAWs he probably wouldn't stop fiddling with it for months or years. Even back in the 60s and 70s I think he was well known to obsess over his recordings, and his practice of occasionally splicing performances to get the best from each take was/is pretty controversial. The irony also being that he was notoriously a pain to record because he often sang overtop his playing.