Absolutely. I often have friends who are working for, or contractors for some company, and get a great opportunity presented to them, and say "but I can't leav

Absolutely. I often have friends who are working for, or contractors for some company, and get a great opportunity presented to them, and say "but I can't leave MegaCorp, I've only been there for a year, and I don't want to let people down". I have to remind them that if their project gets cancelled or postponed, they won't even get two weeks notice from MegaCorp. That they won't let anyone down, MegaCorp has 200 people with your job title. Some companies show real loyalty to their employees, but most will let you go or lay you off without a second thought and without any sleep lost. So why should you lose sleep over turning in your resignation to them.