4 ms·

These are at least 4 known causes of aortic aneurysms. 1) Smoking (behavioral) 2) High blood pressure (dietary or genetic) 3) High cholesterol (dietary of ge

by bb88 4y ago

These are at least 4 known causes of aortic aneurysms. 1) Smoking (behavioral) 2) High blood pressure (dietary or genetic) 3) High cholesterol (dietary of genetic) 4) Marfan's syndrome (genetic) Last I checked, doctors (who know these things) were seriously considering it was #4. You're a skeptic, right? Why invent new untested possibilities when a there are a series of well known possibilities to be tested first?

OrvalWintermute 4y ago
Actually, this list is insufficient according to the NIH [1] an article in Circulation [2] and my wife, a boarded surgeon. Where she provided data I have italicized it, all others are from NIH and the other source. Interestingly, Diabetes can also have a protective effective against aneuryms [3]. There is also evidence that viral infection can likewise play a contributing role to local inflammation in aorta, similar to the better-known effects of bacterial infections ...CMV infection can stimulate local inflammation in the aorta but is not a direct cause of most abdominal aortic aneurysms. [4] Genetic/History Ehlers–Danlos syndrome Loeys–Dietz syndrome Marfan syndrome Turner syndrome Familial thoracic aortic aneurysms Bicuspid aortic valve (BAV), which is an abnormal aortic valve Birth Defect Diabetes, particularly uncontrolled diabetes Lifestyle Habits Aneurysms of blood vessels in other parts of your body Chronic obstructive pulmonary disease (COPD) Cardiovascular conditions, such as atherosclerosis, coronary heart disease, and peripheral artery disease Unhealthy blood cholesterol level High blood pressure, which is the leading risk factor for thoracic aortic aneurysms but also a risk factor for abdominal aortic aneurysm Bacterial infections, which are a risk factor for thoracic aortic aneurysms. Kidney conditions, such as renal failure, chronic kidney disease, and polycystic kidney disease Obesity Pheochromocytoma external link , a rare tumors of the adrenal gland that can lead to high blood pressure Vasculitis [1] https://www.nhlbi.nih.gov/health/aortic-aneurysm/causes https://www.nhlbi.nih.gov/health/aortic-aneurysm/causes [2] https://www.ahajournals.org/doi/10.1161/circulationaha.110.006486 https://www.ahajournals.org/doi/10.1161/circulationaha.110.0... [3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198737/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198737/ [4] https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.26901 https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.26901

by bb88 4y ago

OrvalWintermute 4y ago

Actually, this list is insufficient according to the NIH [1] an article in Circulation [2] and my wife, a boarded surgeon. Where she provided data I have italicized it, all others are from NIH and the other source. Interestingly, Diabetes can also have a protective effective against aneuryms [3]. There is also evidence that viral infection can likewise play a contributing role to local inflammation in aorta, similar to the better-known effects of bacterial infections ...CMV infection can stimulate local inflammation in the aorta but is not a direct cause of most abdominal aortic aneurysms. [4] Genetic/History Ehlers–Danlos syndrome Loeys–Dietz syndrome Marfan syndrome Turner syndrome Familial thoracic aortic aneurysms Bicuspid aortic valve (BAV), which is an abnormal aortic valve Birth Defect Diabetes, particularly uncontrolled diabetes Lifestyle Habits Aneurysms of blood vessels in other parts of your body Chronic obstructive pulmonary disease (COPD) Cardiovascular conditions, such as atherosclerosis, coronary heart disease, and peripheral artery disease Unhealthy blood cholesterol level High blood pressure, which is the leading risk factor for thoracic aortic aneurysms but also a risk factor for abdominal aortic aneurysm Bacterial infections, which are a risk factor for thoracic aortic aneurysms. Kidney conditions, such as renal failure, chronic kidney disease, and polycystic kidney disease Obesity Pheochromocytoma external link , a rare tumors of the adrenal gland that can lead to high blood pressure Vasculitis [1] https://www.nhlbi.nih.gov/health/aortic-aneurysm/causes https://www.nhlbi.nih.gov/health/aortic-aneurysm/causes [2] https://www.ahajournals.org/doi/10.1161/circulationaha.110.006486 https://www.ahajournals.org/doi/10.1161/circulationaha.110.0... [3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198737/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198737/ [4] https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.26901 https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.26901