I believe that significant indentation is only a problem for people whose text editor Tab binding doesn't handle it for them? At least, I've used Python for 15

I believe that significant indentation is only a problem for people whose text editor Tab binding doesn't handle it for them? At least, I've used Python for 15 years and can't think of a problem it's caused me -- what problems are you aware of? It's similar to the people who complain about lisp but are pairing up parens manually. I think the solution in both cases is "don't do that" -- there are perfectly good text editors that do these things for you.