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> The problem is the massive leaps of logic being made by people who have (quite wrongly, based on available evidence) become convinced that the vaccines are a
by __blockcipher__ 4y ago
> The problem is the massive leaps of logic being made by people who have (quite wrongly, based on available evidence) become convinced that the vaccines are a greater threat to healthy people than the virus is.
That may be true overall (and it may not btw, only time will tell), but it's certainly not true on a by-indvidual basis. Someone who's, say, 18 with no major health disorders is going to experience a lot more risk of adverse outcome from any of the vaccines than from SARS-CoV-2. That's partially a function of the incredible SARS-CoV-2 outcomes in the "not old" age range but also because vaccination is also a fundamentally different intervention than exposure to the entire SARS-CoV-2 virus. If we're talking about the mRNA vaccines (Pfizer/moderna/etc), those are basically spike protein mRNA suspended in lipid nanoparticles. It makes your cells express the spike protein, not the whole SARS-CoV-2 virus. So metaphorically speaking you're getting pure spike protein antigen, and different peoples' genetic predispositions/etc are going to play out differently in that scenario as opposed to contact with the normal virus.
...Like those of the people in the case report we're looking at.
- yosame 4y agoYou literally just made the wild leap of logic the parent comment was talking about. The mRNA vaccines have a modified spike protein, that is non functional compared to natural infection. On top of that, cells naturally infected with covid also express the spike protein [1], and would do so in far greater amounts than what would be caused by the vaccine. People's different genetic dispositions will change their immune response, and that might maybe change how they respond to the vaccine as opposed to the virus. But there's no way of knowing which way you will fall, and our current evidence suggests that getting the vaccine is probably always the safer alternative. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941975/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941975/