Admittedly I've not worked in many environments that could ever be described as being anything less than 'enterprise', and within orders of magnitude larger tha

Admittedly I've not worked in many environments that could ever be described as being anything less than 'enterprise', and within orders of magnitude larger than medium/large businesses. If you had a niche market and only needed a small footprint. I can see a handful of VPS' or similar being suitable. But once you get to the 200+ people mark, it gets messy. And gets much worse at 2,000 head. And worse yet at 20,000.