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Any recommendations? I took one that you take at night. It slightly improved my focus during day. But would leave me sleepy all day. Even with taking it befor

Any recommendations? I took one that you take at night. It slightly improved my focus during day. But would leave me sleepy all day. Even with taking it before bed.

thethethethe 4y ago
Wellbutrin worked wonders for me. Works immediately, similar to amphetamines and is easy to obtain legitimately.
- chimeracoder 4y ago
  > is easy to obtain legitimately. Depends on the country. In Europe, it's not so easy. In the UK, the last I checked, it was contraindicated for long-term use, meaning it could be used for smoking cessation but not for long-term ADHD treatment. > similar to amphetamines Wellbutrin has a very different mechanism of action, and a different effectiveness profile. I wouldn't say it's "similar to amphetamines" in any clinical sense.
  - thethethethe 4y ago
    I was just saying it is similar on the sense that it works right away and has a noticeable effect, unlike other depression meds that people take, like SSRIs which take months to kick in
  - professor_meow 4y ago
    > In the UK, the last I checked, it was contraindicated for long-term use, meaning it could be used for smoking cessation but not for long-term ADHD treatment. It is not a typical treatment, but a psychiatrist in the UK does have the discretion to prescribe Bupropion off-label. In my own n=1 experience, as a fourth option, only after unsatisfactory trials of more traditional stimulants and Atomoxetine.
- jstarfish 4y ago
  A counterpoint from my own experience: For me it was like rediscovering caffeine for the first time, which lasted about six months altogether. Then the positive effects waned and it became a self-inflicted case of acid reflux. Would never describe it as being similar to amphetamines. The most praise I can give it is as "an antidepressant that kinda sorta works."
- Zanfa 4y ago
  Didn’t seem to have any significant effect on focus/hyperfocus for me, maybe slightly reduced irritability, but definitely added migraines with aura. Still have them occasionally, even after being off for over a month now.
chrsig 4y ago
Strattera (atomoxetine) is a commonly used SNRI developed for adhd. I personally had a very bad reaction to it, but it allegedly helps some people. Guanfacine is another, I haven't tried it, so I can't give any first hand experience. I think it's used more to help blood pressure & agitation that can come up with adhd Welbutrin is also commonly used.
- tecleandor 4y ago
  I had a bad experience with Strattera too, and now I'm on Vyvanse, which is an amphetamine but not the worst. I'm still on a low dose but not bad. I'm feeling some improvements and thinking about some specialized therapy.
  - s5300 4y ago
    Vyvanse is just DextroAmphetamine once processed in your body - AKA Speed in terms of slang drug usage. AFAIK, it’s just that no matter what the dosage, the drug dispenses itself/processes in your body based on a few factors, & is always that amount being continuously released over time. I guess if you’re arguing (I know you are not, I am just putting unsolicited info out) in terms of what amphetamines are the worst… methamphetamine, pharmaceutical grade & at the equivalent therapeutical dosage for ADHD symptoms - which is something like 5mg-15mg max, & potentially up to 45mg for the very worst cases of chronic fatigue syndrome - is actually less hard than others on your body from a neurotoxicity standpoint, as well as on your vascular system in general. You can also very easily take naps on it (at those dosages). It just happens to be highly addictive because of the whole blood brain barrier crossing thing. & then once you get out of that therapeutic dosage into “recreational/abusive” dosages… that is when meth is very bad. So if you don’t have an addictive personality & can control yourself, prescribed methamphetamine (Desoxyn, not sure if a generic exists) is otherwise the safest treatment for ADHD if expected to be consistently on it for decades/life. I believe it then goes DextroAmphetamine 50:50 Racemic Amphetamine (Evekeo may be brand for this in US?) Adderall (which is 3:1) From least harm on your body to most harm over time. My doc & I for the time being found Vyvanse was nearly perfect for me, & essentially perfected it by adding a small (10mg) instant-release DextroAmphetamine (Zenzedi, specifically branded - seems to be the most perfected formulation in the US pharmacy system as of now.) along with it to kickstart things in the morning. There are also times when I’m scripted to just take multiple 10mg IRs a day instead of the entire Vyvanse dosages for other medical reasons & potential need to rest. Mentioning rest: a non-negligible portion of people on an otherwise perfectly working Vyvanse dosage seem to need a mild-moderate sleep aid towards the end of the day. & where you may think that just indicates a lowering of the dosage, that is mostly wrong & ruins the “otherwise perfectly working” aspect. I only mention all of this unsolicited advice/information as I’ve for far too long now, & with medical practitioners in family, seen anecdote after anecdote of people prescribed Adderall (IR or ER) eventually trying pure DextroAmphetamine IR (previously known as Dexedrine, now Zenzedi, & of course generic) - or ER like Vyvanse - & finding that it works much, much better than Adderall. Typically from a standpoint of less irritability/jitteryness/emotional blunting & more focus & ability to change task to task if needed. For whatever reason though (obviously, industry money slushing around related), Adderall is prescribed at a ridiculously higher rate than pure DextroAmphetamine. There’s also a decent amount of people who’ve only heard the term Adderall & don’t know DextroAmphetamine exists. Finally, that in some rare cases, meth is genuinely the correct drug for treatment. I honestly think if you’re being prescribed an amphetamine, doctors should have to inform you of all amphetamine based medication able to be prescribed for your condition & the potentially pros/cons comparisons - but I am nobody in this world.
astrange 4y ago
Strattera and Tenex are two main ones. They actually have more side effects than amphetamines do, though Strattera works well for me as long as you absolutely always take it with food. (Otherwise it feels like you're getting kicked in the stomach.)
- sbate1987 4y ago
boc 4y ago
I’m not affiliated with these guys at all, and I can’t speak to the long-term effects, but I tried this “flow state” powder mix[1] on a whim and it actually kind of works. It might be placebo but a scoop in the morning after a small cup of coffee has me focusing better than previously. It’s definitely a much more subtle effect vs actual medication. [1]https://promixnutrition.com/products/flow-state https://promixnutrition.com/products/flow-state
hello_newman 4y ago
I am not a doctor, but Modafinil is great. Similar effects to that of Adderall/Ritalin (increased focus, elevated mood, etc) but no major comedown or withdrawal type symptoms. Can get with a prescription or found easily online. Would highly recommend it.

Any recommendations? I took one that you take at night. It slightly improved my focus during day. But would leave me sleepy all day. Even with taking it before bed.

thethethethe 4y ago

Wellbutrin worked wonders for me. Works immediately, similar to amphetamines and is easy to obtain legitimately.

chimeracoder 4y ago
> is easy to obtain legitimately. Depends on the country. In Europe, it's not so easy. In the UK, the last I checked, it was contraindicated for long-term use, meaning it could be used for smoking cessation but not for long-term ADHD treatment. > similar to amphetamines Wellbutrin has a very different mechanism of action, and a different effectiveness profile. I wouldn't say it's "similar to amphetamines" in any clinical sense.
- thethethethe 4y ago
  I was just saying it is similar on the sense that it works right away and has a noticeable effect, unlike other depression meds that people take, like SSRIs which take months to kick in
- professor_meow 4y ago
  > In the UK, the last I checked, it was contraindicated for long-term use, meaning it could be used for smoking cessation but not for long-term ADHD treatment. It is not a typical treatment, but a psychiatrist in the UK does have the discretion to prescribe Bupropion off-label. In my own n=1 experience, as a fourth option, only after unsatisfactory trials of more traditional stimulants and Atomoxetine.
jstarfish 4y ago
A counterpoint from my own experience: For me it was like rediscovering caffeine for the first time, which lasted about six months altogether. Then the positive effects waned and it became a self-inflicted case of acid reflux. Would never describe it as being similar to amphetamines. The most praise I can give it is as "an antidepressant that kinda sorta works."
Zanfa 4y ago
Didn’t seem to have any significant effect on focus/hyperfocus for me, maybe slightly reduced irritability, but definitely added migraines with aura. Still have them occasionally, even after being off for over a month now.

chrsig 4y ago

Strattera (atomoxetine) is a commonly used SNRI developed for adhd. I personally had a very bad reaction to it, but it allegedly helps some people. Guanfacine is another, I haven't tried it, so I can't give any first hand experience. I think it's used more to help blood pressure & agitation that can come up with adhd Welbutrin is also commonly used.

tecleandor 4y ago
I had a bad experience with Strattera too, and now I'm on Vyvanse, which is an amphetamine but not the worst. I'm still on a low dose but not bad. I'm feeling some improvements and thinking about some specialized therapy.
- s5300 4y ago
  Vyvanse is just DextroAmphetamine once processed in your body - AKA Speed in terms of slang drug usage. AFAIK, it’s just that no matter what the dosage, the drug dispenses itself/processes in your body based on a few factors, & is always that amount being continuously released over time. I guess if you’re arguing (I know you are not, I am just putting unsolicited info out) in terms of what amphetamines are the worst… methamphetamine, pharmaceutical grade & at the equivalent therapeutical dosage for ADHD symptoms - which is something like 5mg-15mg max, & potentially up to 45mg for the very worst cases of chronic fatigue syndrome - is actually less hard than others on your body from a neurotoxicity standpoint, as well as on your vascular system in general. You can also very easily take naps on it (at those dosages). It just happens to be highly addictive because of the whole blood brain barrier crossing thing. & then once you get out of that therapeutic dosage into “recreational/abusive” dosages… that is when meth is very bad. So if you don’t have an addictive personality & can control yourself, prescribed methamphetamine (Desoxyn, not sure if a generic exists) is otherwise the safest treatment for ADHD if expected to be consistently on it for decades/life. I believe it then goes DextroAmphetamine 50:50 Racemic Amphetamine (Evekeo may be brand for this in US?) Adderall (which is 3:1) From least harm on your body to most harm over time. My doc & I for the time being found Vyvanse was nearly perfect for me, & essentially perfected it by adding a small (10mg) instant-release DextroAmphetamine (Zenzedi, specifically branded - seems to be the most perfected formulation in the US pharmacy system as of now.) along with it to kickstart things in the morning. There are also times when I’m scripted to just take multiple 10mg IRs a day instead of the entire Vyvanse dosages for other medical reasons & potential need to rest. Mentioning rest: a non-negligible portion of people on an otherwise perfectly working Vyvanse dosage seem to need a mild-moderate sleep aid towards the end of the day. & where you may think that just indicates a lowering of the dosage, that is mostly wrong & ruins the “otherwise perfectly working” aspect. I only mention all of this unsolicited advice/information as I’ve for far too long now, & with medical practitioners in family, seen anecdote after anecdote of people prescribed Adderall (IR or ER) eventually trying pure DextroAmphetamine IR (previously known as Dexedrine, now Zenzedi, & of course generic) - or ER like Vyvanse - & finding that it works much, much better than Adderall. Typically from a standpoint of less irritability/jitteryness/emotional blunting & more focus & ability to change task to task if needed. For whatever reason though (obviously, industry money slushing around related), Adderall is prescribed at a ridiculously higher rate than pure DextroAmphetamine. There’s also a decent amount of people who’ve only heard the term Adderall & don’t know DextroAmphetamine exists. Finally, that in some rare cases, meth is genuinely the correct drug for treatment. I honestly think if you’re being prescribed an amphetamine, doctors should have to inform you of all amphetamine based medication able to be prescribed for your condition & the potentially pros/cons comparisons - but I am nobody in this world.

astrange 4y ago

Strattera and Tenex are two main ones. They actually have more side effects than amphetamines do, though Strattera works well for me as long as you absolutely always take it with food. (Otherwise it feels like you're getting kicked in the stomach.)

sbate1987 4y ago

boc 4y ago

I’m not affiliated with these guys at all, and I can’t speak to the long-term effects, but I tried this “flow state” powder mix[1] on a whim and it actually kind of works. It might be placebo but a scoop in the morning after a small cup of coffee has me focusing better than previously. It’s definitely a much more subtle effect vs actual medication. [1]https://promixnutrition.com/products/flow-state https://promixnutrition.com/products/flow-state

hello_newman 4y ago

I am not a doctor, but Modafinil is great. Similar effects to that of Adderall/Ritalin (increased focus, elevated mood, etc) but no major comedown or withdrawal type symptoms. Can get with a prescription or found easily online. Would highly recommend it.