> the same dangerous theme keeps surfacing: dangerous theme keeps surfacing: monolithic thinking, with “no alternatives allowed” That might be part of it. I th

> the same dangerous theme keeps surfacing: dangerous theme keeps surfacing: monolithic thinking, with “no alternatives allowed” That might be part of it. I think a bigger part is, "we don't know what X is so we can't measure it, but Y seems to coincide with X and we can measure Y, so let's focus on Y". This probably happens a lot and sometimes it works out, but it also often doesn't. It failed with dietary cholesterol, and Alzheimer's is the just the latest big failure of this approach.