That's my noob understanding too. This is a more precise form of autologous transplant. I assume quick adoption of base editing for trickier cases, eg for T-ce

That's my noob understanding too. This is a more precise form of autologous transplant. I assume quick adoption of base editing for trickier cases, eg for T-cell acute lymphoblastic leukemia, like this patient had. Note that she had a previous transplant, using the more conventional treatment of her T cells. Just starting with base editing will be much less onerous to future patients. This is one tough person. Surviving chemo then two transplants is amazing. Just thinking about it crushes my heart. Source: Had bone marrow transplant 30+ years ago. My then experimental treatment became the default option (as applicable). Don't know much about biology or medicine, but I can repeat what I've heard and read.