> when incentives align that provide a significant pressure for them to research what they wouldn't naturally want to research The thing is, the beta amyloid t

> when incentives align that provide a significant pressure for them to research what they wouldn't naturally want to research The thing is, the beta amyloid theory was the only explanation for Alzheimer's that would allow treatments to be developed right now. Tons of people want treatments asap. While it makes no sense to develop treatments based on this theory if they definitely won't work, when it looks like there's an 80% chance of the theory being wrong, 100% of drug companies' Alzheimer's drug development money is still going to go to drugs based on this theory because we have nothing else except vague hypotheses with no drug targets. So actually part of the problem is that so many people are incentivized to keep sticking to this theory and someone needs to step in and stop it.