Well, there's the Pascal-style argument. If you think there's a 10% chance that a Christian God who will send you to hell if you do xyz exists, then, well, tha

Well, there's the Pascal-style argument. If you think there's a 10% chance that a Christian God who will send you to hell if you do xyz exists, then, well, that seems like a very significant risk (compare to a "10% chance of death") and worth taking pains to avoid. On the other hand, if you think it's more like 1 in a million, and furthermore that there's a similar chance of other versions of God or other gods existing who have completely different demands on your behavior, then it's a lot more sensible to say "fuck it, I'm going to ignore such possibilities". Which is a practical difference. I do agree that lots of people would probably do better if they were more comfortable maintaining uncertainty in general.