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Interesting article, I have always wondered about the oversight of animal experimentation at private companies. In my old industry rumors, there is some oversig
by anarticle 4y ago
Interesting article, I have always wondered about the oversight of animal experimentation at private companies. In my old industry rumors, there is some oversight, but because it's private it's not regulated like university research (my xp).
Before animal fans get too upset, know that IACUC exists in the uni sphere which is the vanguard against bad research: https://www.aalas.org/iacuc https://www.aalas.org/iacuc. In short, you have to prove to your local committee why your experiments need animals rather than cell models, in what capacity, and what your standard of care is. It is NOT a rubber stamp org, and they will reject you for any diligence you have missed. IACUC was created the year the Penn monkey helmet experiments were brought to light by PETA, which were abusive. I don't like PETA as an org, but they did good work there.
In the private world, maybe such a thing doesn't exist, or its less prevalent. For sure, even in my time (2000s?) there were rumors of labs contracting research out to other places to escape IACUC oversight. There are strict regs on what you can do to animals, especially primates in the USA.
In my experience, I've seen dogs, macaques, micropigs, xenopus, fruit flies, zebrafish, rats, mice, and even chinchillas in the lab. I've worked with probably half of that list. (USA) They're all extremely valuable models for driving human outcome research. There are tons of examples of fantastic technology derived from animal research. Horseshoe crab blood is a great example, for detection of endotoxin in manufacturing drugs and vaccines. Xenopus frogs used to be used as pregnancy tests in the 30s, as it turns out they will lay eggs if you inject them with small amount of urine. The story of that one is fantastic, recommend a quick perusal if only for how far we've come.
If anything, I'd like to see neuralinks brain in a rack setup come to replace many forms of tissue culture in the lab to push the envelope further and give us more reasons to not use animals in these tests. From a purely capitalist standpoint, animals are WAY more expensive than cell lines, especially mammals.
Also, I can field any questions people have about lab work if you're interested. I'll answer as best I can.