Having had to do that quite frequently in the US, flights from West to East in my experience are much more likely to be non-stop hub to hub, or entirely unavail

Having had to do that quite frequently in the US, flights from West to East in my experience are much more likely to be non-stop hub to hub, or entirely unavailable. The time difference and regional/hopper flights catering to "commuters" who need to fly early morning and late evening doesn't play well with the time zone changes, so you can either have a bunch of hopper flights with full day layovers at each airport, or you can catch an early morning long haul flight from a major hub airport to another major hub airport. In fact I think I just saw an article (can't find the source) that talked about post pandemic the US domestic flights were much more focused on large volume hub-to-hub flights as a way of serving pre-pandemic customer levels despite understaffing.