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Easy, you recognize that with infectious viruses some people will get infected and not show symptoms, and some percentage of people will get sick even though th

Easy, you recognize that with infectious viruses some people will get infected and not show symptoms, and some percentage of people will get sick even though they are vaccinated. This is well known in medicine and in everyday popular culture. The confusion here is your own misunderstanding. - previously deleted this content because it was too aggressive and condescending but adding back since another replied before I could modify - > The other issue is that like other vaccine skeptics if you have a particular issue with mRNA (which doesn’t make sense given you don’t know anything about vaccines, or the differences between mRNA vaccines or other vaccines or even how vaccines work) you could have taken a non-mRNA vaccine.

base698 4y ago
> The other issue is that like other vaccine skeptics if you have a particular issue with mRNA (which doesn’t make sense given you don’t know anything about vaccines, or the differences between mRNA vaccines or other vaccines or even how vaccines work) you could have taken a non-mRNA vaccine. The J&J vaccine was pulled pretty early due to the clotting issues and AZ was not available in the US. It was puzzling to me early on why they'd make a vaccine with a single protein (the case with both mRNA and viral vector vaccine). It seemed obvious a whole virus would have many more opportunities for your body to generate an immune response. Even more puzzling is why China and other countries haven't adopted mRNA vaccines.
- ericmay 4y ago
  > Even more puzzling is why China and other countries haven't adopted mRNA vaccines. Why do you find this puzzling? What countries haven’t adopted mRNA vaccines and what do you mean by “adopted”? > The J&J vaccine was pulled pretty early due to the clotting issues and AZ was not available in the US. And Johnson&Johnson is still available now in the US. They pulled it out of an abundance of caution and because there were other vaccines on the market. If Johnson & Johnson was the only vaccine on the market it wouldn’t have been pulled because of the risk of clotting. -edit- This also doesn’t take into account risk analysis. Extreme likelihood of contracting a highly contagious disease with unknown severity and unknown long-term effects versus the unlikelihood of a blood cloth from Johnson & Johnson’s COVID-19 vaccine. Obviously any casual analysis would show that you’d get the vaccine. > It was puzzling to me early on why they'd make a vaccine with a single protein (the case with both mRNA and viral vector vaccine). It seemed obvious a whole virus would have many more opportunities for your body to generate an immune response. Why would this be puzzling? Can you share some scientific resources that describe the differences in using a “whole virus” versus “part of a virus” and how that affects vaccine effectiveness? I’d like to read the same materials you did.
  - base698 4y ago
    https://scitechdaily.com/scientists-reveal-key-differences-in-immune-response-to-inactivated-virus-and-mrna-covid-19-vaccines/ https://scitechdaily.com/scientists-reveal-key-differences-i... > This also doesn’t take into account risk analysis. Extreme likelihood of contracting a highly contagious disease with unknown severity and unknown long-term effects versus the unlikelihood of a blood cloth from Johnson & Johnson’s COVID-19 vaccine. Obviously any casual analysis would show that you’d get the vaccine. There is a saying in aviation: if it hasn't been out five years you're a test pilot. How did you calculate the unknowns of using a vaccine never deployed widely in humans? In addition there are other ways to avoid the virus, myself I moved to a less populated area. My interactions in public were limited to one about 3 people. Never personally contracted covid until about two months ago. In addition pretty early on it was obvious the high risks were to the obese and elderly. You could have prioritized a more healthy lifestyle. The risk calculation for someone under about sixty doesn't seem that straight forward, and hedges primarily on how scared you are of the virus vs an industry that routinely kills it's customers and lies about it.
    - ericmay 4y ago
      > There is a saying in aviation: if it hasn't been out five years you're a test pilot. How did you calculate the unknowns of using a vaccine never deployed widely in humans? We routinely widely deploy vaccines. The flu vaccine, vaccines for newborns and children, etc. > In addition there are other ways to avoid the virus, myself I moved to a less populated area. My interactions in public were limited to one about 3 people. Never personally contracted covid until about two months ago. In addition pretty early on it was obvious the high risks were to the obese and elderly. You could have prioritized a more healthy lifestyle Alternatively I’ve been vaccinated, and boosted twice, and maintain a health lifestyle and haven’t contracted COVID-19 that I’m aware of while living in a city, interacting with other people, and traveling. These are just anecdotes and don’t generalize. There are also people who are “perfectly healthy” who get severely ill, some people who didn’t know they had an underlying medical condition who died, and people who were otherwise healthy suffering from long COVID. I’m surprised it’s not very clear to you here that you are not in control. Rural areas were some of the hardest hit because of vaccine skepticism. “It’s ok for me to smoke cigarettes because so and so smoked a pack a day and lived to be 100” > The risk calculation for someone under about sixty doesn't seem that straight forward, and hedges primarily on how scared you are of the virus vs an industry that routinely kills it's customers and lies about it. It seems pretty straightforward. You get a vaccine and then you most likely don’t get COVID, or if you do the severity of the virus is typically not as bad as it could be, or you don’t get the vaccine and you roll the dice for no real reason. > https://scitechdaily.com/scientists-reveal-key-differences-in-immune-response-to-inactivated-virus-and-mrna-covid-19-vaccines/ https://scitechdaily.com/scientists-reveal-key-differences-i... Ok but what is puzzling about this?

base698 4y ago

> The other issue is that like other vaccine skeptics if you have a particular issue with mRNA (which doesn’t make sense given you don’t know anything about vaccines, or the differences between mRNA vaccines or other vaccines or even how vaccines work) you could have taken a non-mRNA vaccine. The J&J vaccine was pulled pretty early due to the clotting issues and AZ was not available in the US. It was puzzling to me early on why they'd make a vaccine with a single protein (the case with both mRNA and viral vector vaccine). It seemed obvious a whole virus would have many more opportunities for your body to generate an immune response. Even more puzzling is why China and other countries haven't adopted mRNA vaccines.

ericmay 4y ago
> Even more puzzling is why China and other countries haven't adopted mRNA vaccines. Why do you find this puzzling? What countries haven’t adopted mRNA vaccines and what do you mean by “adopted”? > The J&J vaccine was pulled pretty early due to the clotting issues and AZ was not available in the US. And Johnson&Johnson is still available now in the US. They pulled it out of an abundance of caution and because there were other vaccines on the market. If Johnson & Johnson was the only vaccine on the market it wouldn’t have been pulled because of the risk of clotting. -edit- This also doesn’t take into account risk analysis. Extreme likelihood of contracting a highly contagious disease with unknown severity and unknown long-term effects versus the unlikelihood of a blood cloth from Johnson & Johnson’s COVID-19 vaccine. Obviously any casual analysis would show that you’d get the vaccine. > It was puzzling to me early on why they'd make a vaccine with a single protein (the case with both mRNA and viral vector vaccine). It seemed obvious a whole virus would have many more opportunities for your body to generate an immune response. Why would this be puzzling? Can you share some scientific resources that describe the differences in using a “whole virus” versus “part of a virus” and how that affects vaccine effectiveness? I’d like to read the same materials you did.
- base698 4y ago
  https://scitechdaily.com/scientists-reveal-key-differences-in-immune-response-to-inactivated-virus-and-mrna-covid-19-vaccines/ https://scitechdaily.com/scientists-reveal-key-differences-i... > This also doesn’t take into account risk analysis. Extreme likelihood of contracting a highly contagious disease with unknown severity and unknown long-term effects versus the unlikelihood of a blood cloth from Johnson & Johnson’s COVID-19 vaccine. Obviously any casual analysis would show that you’d get the vaccine. There is a saying in aviation: if it hasn't been out five years you're a test pilot. How did you calculate the unknowns of using a vaccine never deployed widely in humans? In addition there are other ways to avoid the virus, myself I moved to a less populated area. My interactions in public were limited to one about 3 people. Never personally contracted covid until about two months ago. In addition pretty early on it was obvious the high risks were to the obese and elderly. You could have prioritized a more healthy lifestyle. The risk calculation for someone under about sixty doesn't seem that straight forward, and hedges primarily on how scared you are of the virus vs an industry that routinely kills it's customers and lies about it.
  - ericmay 4y ago
    > There is a saying in aviation: if it hasn't been out five years you're a test pilot. How did you calculate the unknowns of using a vaccine never deployed widely in humans? We routinely widely deploy vaccines. The flu vaccine, vaccines for newborns and children, etc. > In addition there are other ways to avoid the virus, myself I moved to a less populated area. My interactions in public were limited to one about 3 people. Never personally contracted covid until about two months ago. In addition pretty early on it was obvious the high risks were to the obese and elderly. You could have prioritized a more healthy lifestyle Alternatively I’ve been vaccinated, and boosted twice, and maintain a health lifestyle and haven’t contracted COVID-19 that I’m aware of while living in a city, interacting with other people, and traveling. These are just anecdotes and don’t generalize. There are also people who are “perfectly healthy” who get severely ill, some people who didn’t know they had an underlying medical condition who died, and people who were otherwise healthy suffering from long COVID. I’m surprised it’s not very clear to you here that you are not in control. Rural areas were some of the hardest hit because of vaccine skepticism. “It’s ok for me to smoke cigarettes because so and so smoked a pack a day and lived to be 100” > The risk calculation for someone under about sixty doesn't seem that straight forward, and hedges primarily on how scared you are of the virus vs an industry that routinely kills it's customers and lies about it. It seems pretty straightforward. You get a vaccine and then you most likely don’t get COVID, or if you do the severity of the virus is typically not as bad as it could be, or you don’t get the vaccine and you roll the dice for no real reason. > https://scitechdaily.com/scientists-reveal-key-differences-in-immune-response-to-inactivated-virus-and-mrna-covid-19-vaccines/ https://scitechdaily.com/scientists-reveal-key-differences-i... Ok but what is puzzling about this?